Nociception Flashcards

1
Q

________: itch

A

Pruritis: itch

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2
Q

Test for Spinocervicothalamic Pathway

A

Light and brief pinching of the skin

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3
Q

__________ fibers innervates both superficial and deep pain pathways

A

Both fibers innervates both superficial and deep pain pathways

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4
Q

Chronic pain produces long term changes that create (greater/lesser) sensitivity to stimuli

A

Chronic pain produces long term changes that create (greater/lesser) sensitivity to stimuli

______________

Chronic pain patients become more painful over time

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5
Q

____________: indescriminant ascending nociceptive pathway

A

Spinoreticular Pathway: indescriminant ascending nociceptive pathway

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6
Q

T/F: General Visceral Afferents (GVA) are very descriminant

A

False

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7
Q

________ pain resulting from injury of the nervous system

A

Neuropathic pain resulting from injury of the nervous system

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8
Q

_________________ change body chemistry to decrease pain pathway.

A

Descending Modulatory Pathway change body chemistry to decrease pain pathway.

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9
Q

Neuropathic pain and dysesthesia mainifest as __________ in veterinary medicine.

A

Neuropathic pain and dysesthesia mainifest as self-mutilation in veterinary medicine.

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10
Q

Subcortical stimulation by the spinoreticular pathway provides __________ to pain

A

Subcortical stimulation by the spinoreticular pathway provides emotional response to pain

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11
Q

___________: control pain by augmenting descedning modulating systems.

A

Opiods and Alpha-Adrenergics: control pain by augmenting descedning modulating systems.

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12
Q

____________: discriminate ascending nociceptive pathway.

A

Spinocervicothalamic Pathway: discriminate ascending nociceptive pathway.

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13
Q

___________: control pain by inhibiting spinal cord sensitization

A

NMDA Inhibitors: control pain by inhibiting spinal cord sensitization

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14
Q

Pain reception is (voluntary/involuntary)

A

Pain reception is (voluntary/involuntary)

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15
Q

Somatic structure ratio of A delta : C fibers

A

1:2

_______________

descriminant

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16
Q

__________: decreased perception of pain

A

Hypoalgesia: decreased perception of pain

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17
Q

Test for the Spinoreticular tract

A

Pinch nail bed

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18
Q

___________: neurons that respond to noxious and non-noxious stimuli, associated with referred pain

A

Wid-Dynamic Range (WDR): neurons that respond to noxious and non-noxious stimuli, associated with referred pain

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19
Q

Nociceptive fiber types

A

A delta Fibers

C Fibers

20
Q

____________: use gate control theory to control pain

A

Water therapy, Massage, Acupuncture: use gate control theory to control pain

21
Q

Bradykinin, Serotonin and Potassium (stimulate/inhibit) nociceptors

A

Bradykinin, Serotonin and Potassium (stimulate/inhibit) nociceptors

22
Q

Visceral structure A delta : C fiber

A

1:10

_________________

mostly dull/throbbing indescriminate pain

23
Q

__________: persist beyond expected time frame for a given disease/injury, usually present for longer than 3-6 months

A

Chronic Pain: persist beyond expected time frame for a given disease/injury, usually present for longer than 3-6 months

24
Q

___________: non-noxious stimulation can help reduce perception of pain

A

Gate Control Theory: non-noxious stimulation can help reduce perception of pain

25
Q

__________ fibers are fast conducting and myelinated. Responsible for sharp, prickling pain.

A

A delta fibers are fast conducting and myelinated. Responsible for sharp, prickling pain.

26
Q

Spinocervicothalamic Pathway = ______________

A

Spinocervicothalamic Pathway = Superficial Pain Pathway

27
Q

Spinoreticular Pathway = ____________

A

Spinoreticular Pathway = Deep Pain Pathway

28
Q

________: modulate/ prevent the transduction of nociceptor

A

NSAID’s: modulate/ prevent the transduction of nociceptor

29
Q

____________ is associated with inflammation and increases sensitivity of nocicepters, contribute to development of hyperalgesia and allodynia.

A

Substance P is associated with inflammation and increases sensitivity of nocicepters, contribute to development of hyperalgesia and allodynia.

30
Q

___________: detection of noxious stimuli through activation of nociceptors

A

Nociception: detection of noxious stimuli through activation of nociceptors

31
Q

__________: non-noxious stimuli activates nociceptors

A

Allodynia: non-noxious stimuli activates nociceptors

32
Q

Prostaglandins and leukotrienes (increase/decrease) the threshold of nociceptors

A

Prostaglandins and leukotrienes (increase/decrease) the threshold of nociceptors

33
Q

Describe the Spinoreticular Pathway

A

Primary Afferent → Dorsal Horn → Dorsolateral fasiculus → ventral/lateral funicululi → Reticular formation → 1. Cortical or 2. Subcortical

_________________

Many decussations occur in this area

34
Q

___________: unpleasant sensation associated with neuropathic pain.

A

Dysenthesia: unpleasant sensation associated with neuropathic pain.

35
Q

___________: absence of all sensory perception, decreased cortical perception of pain but pain is still occuring.

A

Anesthesia: absence of all sensory perception, decreased cortical perception of pain but pain is still occuring.

36
Q

__________ is responsible for awakeness and alertness. Link between sensory stimulation and arousal

A

ARAS is responsible for awakeness and alertness. Link between sensory stimulation and arousal

37
Q

_______: interfere with conduction of nociceptor stimuli at the CNS

A

Local Blocks, Anesthesia: interfere with conduction of nociceptor stimuli at the CNS

38
Q

__________: complete absence of pain perception

A

Analgesia: complete absence of pain perception

39
Q

Connection of pain pathways to the __________ ensures negative emotional response to pain.

A

Connection of pain pathways to the limbic system ensures negative emotional response to pain.

40
Q

__________: controls pain by decreasing perception of pain, should not be sole treatment.

A

Sedation: controls pain by decreasing perception of pain, should not be sole treatment.

41
Q

___________: target WDA and NMDA receptors to decrease amplified nervous system stimulation to pain pathway.

A

Wind Up: target WDA and NMDA receptors to decrease amplified nervous system stimulation to pain pathway.

42
Q

Describe the Spinocervicothalamic Pathway

A

Primary Afferent → Dorsal Horn → Lateral funiculus → Lateral cervical nucleus (deccussation) → Medial Lemniscus → Thalamus → Cortex

_________________

Occurs contralaterally

43
Q

_________: arises from trauma or inflammation

A

Acute Pain: arises from trauma or inflammatio

44
Q

___________ occurs at skin and mucous membranes. Thought to be due to subsets of A delta and C fibers.

A

Pruritis occurs at skin and mucous membranes. Thought to be due to subsets of A delta and C fibers.

45
Q

_______ fibers are slow conducting and unmyelinated. Responsible for burning or throbbing pain.

A

C fibers are slow conducting and unmyelinated. Responsible for burning or throbbing pain.