UsefulNotesDrugs

Question 1

Useful notes on Midazolam

Answer 1

synergy with narcotics, same IV dose regardless of weight

Question 2

Useful notes on Fentanyl

Answer 2

bradycardia > morphine, synergism with benzos, 100x potent as morphine, hemodynamic stability

Question 3

Useful notes on Morphine

Answer 3

often diluted from 10 mg/ml to 1 mg/ml

Question 4

Useful notes on Hydromorphone

Answer 4

not as much PONV as morphine

Question 5

Useful notes on Naloxone

Answer 5

dilute 0.4 mg vial in 10 ml and give 1 ml at a time

Question 6

Useful notes on Propofol

Answer 6

burns on injection, decreases PONV, short duration from redistribution, dose dependent decrease in respirxn, little analgesia

Question 7

Useful notes on Etomidate

Answer 7

cardiovasvular stability, used with bad hearts or HTN

Question 8

Useful notes on Ketamine

Answer 8

nystagmus, prolongs SUX duration

Question 9

Useful notes on Succinylcholine

Answer 9

causes fasciculations, metabloized by plasma cholinesterase, many adverse side effects

Question 10

Useful notes on Rocuronium

Answer 10

increased duration with liver disease and pregnancy, metabolized by liver/kidneys, use TOF for maint and give 1 ml at a time

Question 11

Useful notes on Vecuronium

Answer 11

hardly used for intubation b/c of long onset, use TOF for maint and give 1 ml at a time

Question 12

Useful notes on Cisatracurium

Answer 12

good for renal/hepatic dysfunction, undergoes Hoffman degradation

Question 13

Useful notes on Neostigmine

Answer 13

dosage based on twitch monitor, BLUDS caused at muscarinic cholinergic receptor sites

Question 14

Useful notes on Glycopyrrolate

Answer 14

used specifically to counteract BLUDS, used w/ neostigmine b/c of similar onset/duration, 80 kg pt -> 8.0 -> 4.0 ml neo, 4.0 ml glyco

Question 15

Useful notes on Epinephrine

Answer 15

effects ? & ? receptors

Question 16

Useful notes on Ephedrine

Answer 16

mainly indirect action by causing NE release

Question 17

Useful notes on Phenylephrine

Answer 17

direct acting binds to ? receptors, caution w/ bad hearts b/c of increased afterload, no ? effect, occ. combined with glycopyrrolate

Question 18

Useful notes on Esmolol

Answer 18

fast onset/short duration, works only on ?1 receptors of heart ? ?HR/contractility ? ?BP, metabolized by plasma cholinesterase

Question 19

Useful notes on Metoprolol

Answer 19

same effect as Esmolol, but lasts longer

Question 20

Useful notes on Labetalol

Answer 20

?:? antagonism 7:1, vasodilation from blocking ?1

Question 21

Useful notes on Nitroglycerin

Answer 21

fast onset/short duration, no effect on heart only vasculature, mainly venous side, ? ventricular wall tension

Question 22

Useful notes on Hydralazine

Answer 22

no effect on heart only vasculature, mainly arterial side, long duration undesirable with blood loss

Question 23

Useful notes on Ondansetron

Answer 23

give 30 min before emergence, have PO version for morning sickness, sometimes pushed with induction for short cases

Question 24

Useful notes on Droperidol

Answer 24

used mainly as a secondary to Zofran