XXII - Sedative Hypnotics Flashcards Preview

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Flashcards in XXII - Sedative Hypnotics Deck (15)
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1
Q

Acute anxiety attacks, anesthesia induction, preoperative sedation

A

Midazolam

2
Q

Seizure disorders (status epilepticus), alcohol withdrawal, tranquilizer

A

Diazepam

3
Q

Date-Rape Drugs

A

Alcohol, Flunitrazepam (Rohypnol), Gamma-hydroxybutyrate

4
Q

Antidote to benzodiazepine overdose

A

Flumazenil

5
Q

Anesthesia induction, lethal injection, truth serum

A

Thiopental

6
Q

Seizure disorders in children, SE: precipitates porphyria, CYP450 inducer

A

Phenobarbital

7
Q

Cl-Channel Effects: Benzodiazepines

A

↑ frequency

8
Q

Cl-Channel Effects: Barbiturates

A

↑ duration

9
Q

Abnormal sleep pattern from benzodiazepines

A

↓ REM sleep

10
Q

Benzodiazepine with the longest half-life

A

Chlordiazepoxide

11
Q

Barbiturate with the shortest half-life

A

Thiopental

12
Q

Most catastrophic symptom of sedative-hypnotic withdrawal

A

rebound suicide

13
Q

Sleep disorders

A

Zolpidem, Zaleplon

14
Q

Generalized anxiety disorders, onset of 2 weeks, acts like a benzodiazepine

A

Buspirone

15
Q

Sedative-Hypnotic Poisoning

A

Hypothermia, Hypotension, Hypoactive BS, Disinhibition, Coma, Nystagmus