XIX - Female Genital System and the Breast Flashcards Preview

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Flashcards in XIX - Female Genital System and the Breast Deck (173)
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121

Earliest lesions consist of red papules progressing to vesicles then to painful coalescent ulcers on the vulvar or vaginal area. Smears shows multinucleated squamous cellswith basophilic viral inclusion with a ground-glass appearance. This is caused by:

HSV (TOPNOTCH) Robbins Basic Pathologym 9th ed, p. 993

122

Presents with pearly, dome-shaped papules with a dimpled center. Central waxy core contains cells with cytoplasmic viral inclusion. The lesion described is:

Molluscum contagiosum(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 993

123

Manifests with vulvovaginal pruritus, erythema, swelling, and curdlike vaginal discharge. Wet KOH mount of discharge shows pseudospore or filamentous fungal hyphae.

Candidiasis(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 994

124

Presents with yellow, frothy vaginal discharge, vulvovaginal discomfort, dysuria, and dyspareunia. The vaginal and cervical mucosa typically has a fiery red appearance, with marked dilatation of cervical mucosal vessels ("strawberry cervix"). The cause is:

Trichomonas vaginalis(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 994

125

Presents with thin, green-gray, fishy vaginal discharge. Pap smear reveal squamous cells covered with a shaggy coating coccobacilli.

Bacteria vaginosis(caused by Gardnerella vaginalis)(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 994

126

This infection is characterized by marked acute inflammation of mucosa; smears of inflammatory exudate shows phagocytosed gram-negative diplococci within neutrophils.

Gonococcal infection(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 995

127

Most common site of vaginal carcinoma

Upper vagina, posterior wall at the junction with ectocervix(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1000

128

True or False: All HSILS are considered to be at high risk for progression to carcinoma.

True(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 1003

129

Viral proteins implicated in the ability of HPV to act as carcinogen by interfering with the activity of tumor suppressor proteins.

E6 and E7(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1002

130

Most common histologic subtype of cervical carcinoma

Squamous Cell Carcinoma (TOPNOTCH)

131

Most common high-risk HPV type causing cervical precursor lesions and cervical carcinomas.

HPV-16.(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1007

132

Most frequent cause of dysfunctional bleeding

Anovulation(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1009

133

Disease of women in active reproductive life; causes infertility, dysmenorrhea, pelvic pain. Endometrial glands and stroma outside of the uterus.

Endometriosis (TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 1012

134

An important cause of abnormal uterine bleeding; frequent precursor to endometrial carcinoma; most commonly caused by by unopposed estrogen stimulation.

Endometrial hyperplasia (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1013

135

Most common invasive cancer of the female genital tract

Endometrial carcinoma(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1013

136

True or False. Malignant transformation of leiomyoma to leiomyosarcoma is rare.

True(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 1020

137

The majority of ovarian neoplasm arise from?

Mullerian epithelium(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1023

138

The most common primary malignant ovarian tumor

Serous adenocarcinoma(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1023

139

Most common germ cell tumor of the ovary in women of reproductive age

Mature cystic teratoma/dermoid cyst(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1031

140

Glomerulus-like structure composed of a central blood vessel enveloped by tumor cells within a space lined by tumor cells

Schiller-Duval body(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1031

141

Characteristic histologic feature of Yolk Sac Tumor

Schiller-Duval body(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1031

142

Ovarian tumor that may elaborate large amounts of estrogen; Two thirds occur in post-menopausal women; potentially malignant

Granulosa cell tumor(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1032

143

Biomarker useful for identifying granulosa an other sex cord-stromal tumors, and monitoring treatment.

Serum inhibin(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1032

144

Serum marker for ovarian carcinoma

CA-125(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1029

145

Ovarian tumor that often functional and commonly produce masculinization or defeminization; peak incidence 20-30 y/o; cut surface is usually solid, gray to golden brown in appearance.

Sertoli-Leydig cell tumor(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. `033

146

Most common extra-mullerian tumors metastatic to the ovary

Carcinoma of the breast and GIT(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1034

147

Systemic syndrome characterized by widespread maternal endothelial dysfunction that presents during pregnancy with hypertension, edema, and proteinuria.

Preeclampsia(TOPNOTCH) Robbins Basic Pathology, p. 1034

148

Morphology: placental infarcts, retroplacental hematoma, abnormal decidual vessels, fibrin thrombi in the portal capillaries and hemorrhagic necrosis of the liver, kidney glomeruli show marked swelling of endothelial cells, mesangial cell hyperplasia, amorphous dense deposits on the endothelial side of basement membrane.

Preeclampsia(TOPNOTCH) Robbins Basic Pathology, p. 1039

149

Choriocarcinoma is most often preceded by:

Complete H. mole(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1041

150

Most common cause of acute bacterial mastitis

Staphylococcus aureus(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 1046

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