Flashcards in Viruses Deck (6)
What conditions are associated with Coxsackie A?
Hand, foot, and mouth disease
Acute hemorrhagic conjunctivitis
What conditions are associated with Coxsackie B?
What is the pathogenesis of orthomyxoviridae?
Hemagglutinin on viral cell binds to sialic acid on host cell. When virus is being exocytosed, NA cleaves it.
What is antigenic drift?
Small, constant point mutations
Gradual change in amino acid composition
Results in minor antigenic change leading to EPIDEMICS
Seen in all 3 types of influenza
What is antigenic shift?
Substitution of gene segments with segments from another influenza virus from a different host --> reassortment
Only seen in influenza A