Viral skin (lec 21) Flashcards

1
Q

Rubeola is?

Route of infection?

A

measles

Multipl in resp epith/lymph nodes
Spread via monocytes thru blood

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2
Q

Rubeola signs/sxs?

A

Prodrome: high fever, coryza, cough, conjunctivitis
Koplik’s spots
Rash (starts central)
↑ antibody titers

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3
Q

Rubeola complications?

A

PNA
Diarr
Encephalitis

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4
Q

Rubeola epidemiology?

A

humans, monkeys
(U) kids
resp drop transm

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5
Q

Rubeola dx?

A

rash/Koplik

FA test

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6
Q

Rubeloa vaccine?

A

MMR II

live

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7
Q

Rubella is?

Presentation?

A

German measles

mild rash

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8
Q

Rubella complications?

A

Congenital Rubella Synd:

CV, sight, hearing defects

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9
Q

Rubella vaccine?

A

MMR

live

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10
Q

HSV disease capacity?

A

1) invade/replicate in CNS

2) cause latent infections (in dorsal root gangl)

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11
Q

HSV diagnostics?

A

Tzanck stain

Ballooning pathology

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12
Q

Chickenpox/Shingles caused by?

A

Varicella-Zoster V

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13
Q

Varicella presentation?

A

asymmetrical vesicular rash
(follows dermatome)
PRURITIC
viral sxs

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14
Q

Varicella route of infect?

A

conjunctiva or resp tract mucosa

replicates in lymph nodes -> ºviremia

replicated in liver/spleen -> 2º viremia w/ rash

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15
Q

Varicella epidemiology?

A

Humans
Winter/Spring
U 5-9 yo
Spread thru resp secretion and vesicles

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16
Q

Varicella tx?

A

NO ASPRIN (Reyes)

If severe, acyclovir

17
Q

Shingles caused by?

A

recrudesce of Zoster

18
Q

Shingles complications?

A

neuralgia

19
Q

Human Herpes Virus 6 (HHV6) causes?

Presentation?

A

Roseola Infantum/6th disease

High fever followed by rash

20
Q

HHV6 diagnostics?

A

EIA (antibody detection)

PCR (DNA detection)

21
Q

HHV6 tx?

A

none

no vaccine

22
Q

Parvovirus B19 causes?

A

5th Disease/Erythema Infectiosum

23
Q

5th Disease presentation?

A

Prodrome w/ mild viral sxs
Rash follows: “slapped cheek”, spares mouth

ADULT: (P) just arthritis w/o prodrome or rash

24
Q

5th Disease complications?

A

Rash on limbs/trunk

CT arthralgia: hands/feet, knees, ankles

25
Q

5th Disease diagnostics?

A

antiB19 IgM antibody

26
Q

HPV causes?

A

6/11: genital warts

16/18: cervical dysplasia