Flashcards in Unit 7 - Female Reproduction Case Studies Deck (7)
what is menopause typically diagnosed by?
rise in circulating FSH
why doesn't ovulation occur in polycystic ovary syndrome?
no dominant follicle emerges, although multiple primordial follicles are present
-many cysts in ovaries may prevent maturation during follicular phase
what is PCOS characterized by?
-reduced estrogen by granulosa cells
-reduced progesterone by granulosa and thecal cells
-continued production of androgen by thecal cells throughout the cycle
-irregular/absent menses (have thin endometrial tissue)
what are treatments for PCOS?
-birth control (estrogen and progesterone) to restore menses
-Clomiphene to restore ovulation
-5-alpha-reductase inhibitors to block testosterone --> DHT
-weight loss to control abnormal blood glucoes and diminished insulin sensitivity
what is the "leading theory" for endometriosis?
what is the most dangerous region for rupture during ectopic pregnancies?
interstitial area ruptures at 12-16 weeks gestation
-this is closest to the arteries, so there is a greater risk for massive hemorrhage