Transfusion Medicine and Granulocyte Disorders Flashcards Preview

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Flashcards in Transfusion Medicine and Granulocyte Disorders Deck (52)
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1

Storage of Whole Blood

35 days/4-6C

2

Storage of PRBCs

35 days/4-6C

3

A left shift in the WBC differential indicates a ______ in neutrophils and a _______ in lymphocytes.

increase; decrease

4

A right shift in the WBC differential indicates a ______ in neutrophils and a _______ in lymphocytes.

decrease; increase

5

Adult neutrophilia ANC

>7500/mcL

6

Blood product used for increasing oxygen capacity to treat low HCT patients

PRBCs

7

Blood product used for low or absent fibrinogen associated with disorders and replacement for factor XIII deficiency

Cryoprecipitate

8

Blood product used for severe bacterial or fungal infection in patients with ANC <500/μL

Granulocyte concentrates

9

Blood product used to in assive transfusions to replace oxygen carrying capacity and blood volume

Whole Blood

10

Blood product used to treat bleeding associated with thrombocytopenia or platelet dysfunction

Platelets

11

Blood product used to treat coagulopathy related to procoagulant deficiency

FFP

12

Child/Adolescent/Adult ANC

<1500/mcL

13

Defect in which complement factor(s) describes the following symptoms: recurrent bacterial infections?

C3

14

Defect in which complement factor(s) describes the following symptoms: severe infections with Neisseria

C5-C9

15

Defect in which complement factor(s) describes the following symptoms: SLE, autoimmunity, and inflammatory vascular disease?

C1q, C2, C4

16

Eosinophil Count for Eosinophilia

>350/mcL

17

For severe cases, _______ at a dose of 3-5mcg/kg subcutaneously every day will normalize production of neutrophils.

G-CSF

18

HCT of PRBCs

70%

19

Infant neutropenia ANC

<1100/mcL

20

Monocyte Count for Monocytosis

>500 (Child/adult), >1000 (newborn)

21

Newborn neutropenia ANC

<3000/mcL

22

Newborn neutrophilia ANC

>13,000/mcL

23

Storage of Cryoprecipitate

18 hours/4C then 1 year/-18C

24

Storage of FFP

1 year/18C

25

Storage of Granulocyte Concentrate

8-12hours/Room temp

26

Storage of Platelet Concentrate

22-24C/5-7days

27

The adverse reaction characterized by alloantibody production and slow destruction of sensitizing cells is _______

Delayed hemolytic Transfusion reaction

28

The adverse reaction characterized by infiltrates, dyspnea, and difficulty maintaining peripheral oxygen saturation is ________.

Transfusion-Related Lung Injury (TRALI)

29

The adverse reaction involving bronchospasm that is frequently seen in IgA-deficient individuals is _______.

Anaphylactic reaction

30

The adverse reaction likely to occur with incompatible blood products is _______.

Immediate hemolytic transfusion reaction