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Flashcards in Topical Antiparasitic Agents Deck (5)
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1
Q

How is permethrin metabolized and excreted ?

A

Metabolized Through ester cleavages and virtually all of absorbed permethrin is excreted via urine within one week

2
Q

Permethrin MoA

A

Reported to act on the cell membrane of Arthropods by disabling the sodium transport mechanism, which is responsible for maintenance of polarization of arthropod neuro membranes

Scabies mite is paralyzed

3
Q

Permethrin 3% cream is the treatment of choice for scabies

A

False 5%

4
Q

Permethrin is a synthetic pyrethroid , which are like natural pyrethrins (derived from Compositae; a relative of crysanthemum)

A

T

5
Q

Malathion inhibits glutamate gates chloride ion channels leading to neuromuscular paralysis in Arthropods

A

False
Inhibits acetylcholine
Ivermectin inhibits chloride ion channels