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Flashcards in TM Deck (72)
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1

How many platelets in a pheresis unit?

3 x10^11

2

Minimum donor intervals RBC

>=8 weeks for single unit whole blood donation
16 weeks if double unit by apheresis

3

bombay phenotype

Lacks H and secretor genes (hh, sese)

4

What sugar makes A antigen

Gal-NAc (N-acetylgalactosamine)

5

What sugar makes B antigen?

galactose (Gal)

6

what minor red cell antibody is most common cause of ABO discrepancy?

Anti-M (IgM)
*Redo ABO testing with M neg cells

7

What infection associated with Anti-I autoantibody?

Mycoplasma pneumonia

8

What infection associated with anti-i autoantibody?

infectious mononucleosis

9

PCH caused by what antibody?

Auto anti-P

10

Most common Weiner haplotype in caucasians?

R1 DCe

11

Most common Weiner haplotype in african americans?

R0 Dce

12

duffy negative confers resistance to what?

P. vivax

13

3 possibilities of RhD+ person showing anti-D?

1. Variant/partial D (weak D testing will pick up)
2. Auto-antibody (DAT +)
3. Anti-LW antibody (DAT -)

14

Which antibodies show dosage

Kids, Monkeys (Rh) and MeN Show Dosage
-->Kidd, Rh, MNS and Duffy

15

Which antibody shows anamnestic response?

Kidd system (kids hide)

16

Which antibodies are enhanced by enyzmes?

Give sugar (CHO antigens) to Kids and monkeys (Rh) and they will jump

Rh
Kidd
Le, I, P, ABO

17

Which antibodies are decreased by enyzmes?

Daffy MeNS Lutheran Choir falls down

Duffy
MNS
Lu
Chido-Rogers

18

Which antibodies are unaffected by enyzmes?

Kell (doesn't care)

19

RBC/Whole blood storage

21 days (CPD/2D)
35 days (CPDA-1)
42 days (AS_
all @1-6C

20

Frozen RBC storage

10 yrs @-65C
24 hrs @1-6C after thaw

21

Washed RBC storage

24 hrs @1-6 C

22

Platelet storage

5 days @20-24 C (gentle agitation)
4 hours if pooled in open system

23

granulocyte storage

24 hrs 20-24C (no agitation)

24

FFP stroage

1 year @-18C
7 years @ -65C
24 hrs at 1-6 C after thaw

25

Cryo storage

1 year @-18C
6 hrs @20-24C after thaw (4 hours in pooled open system)

26

RBC quality control

HCT <80% all
>50g Hb in 95% (apheresis RBC)

27

Quality control leukoreduced RBCs

<5x10^6 WBCs in 95%, retain 85% of RBCs

28

Quality control cryo

factor 8>80IU, fibrinogen >150 mg

29

RBC storage lesion

Decreased 2,3 DPG
Decreased ATP
Decreased pH
Decreased K+ in red cells, but increased K+ extracellularly

30

Minimum interval for donation apheresis platelet

Platelets apheresis <= 2 donations/week at least 2 days apart (<=24 in 12 mo period)