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Flashcards in Thrombotic Disease Deck (11)
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1

What is a stroke?

Occurs when there is a rapid death of brain tissue die to a disturbance in the blood supply
Thrombus formation may block blood flow - stops brain getting the oxygen and nutrition it needs
Persists beyond 24 hours

2

What is a transient ischaemic attack (TIA)?

A mini stroke
Symptoms resolve completely after 24 hours

3

List 5 factors for stroke

1. Inactivity
2. High BP
3. Heart disease
4. Smoking - damages endothelium = collagen = releases platelets
5. Obesity

4

How is blood supplied to the brain?

1. Carotid arteries
2. Vertebral arteries
3. Basilar artery
4. Communicating arteries

5

What is the role of the communicating arteries?

Used for cross-over flow when damage in one of the arteries

6

What is the role of the Circle of Willis

Anterior communicating artery allows temporary blood flow to areas of the brain where the blood supplied is blocked

7

What causes a thrombosis

When the atherosclerotic plaque ruptures
This interrupts blood supply to the neurons
Rapid death of brain tissues leads to loss of brain function

8

Define: Ischemia

Starving of oxygen
Mainly due to thrombosis

9

List 2 causes of an ischemic stroke

1. Thrombosis
2. Embolism

10

What is an embolism?

Portion of a blood clot (embolus) can travel to the brain and stop the blood flow
Heart is the common source of embolisms

11

What are the 2

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