Flashcards in Thrombotic Disease Deck (11)
What is a stroke?
Occurs when there is a rapid death of brain tissue die to a disturbance in the blood supply
Thrombus formation may block blood flow - stops brain getting the oxygen and nutrition it needs
Persists beyond 24 hours
What is a transient ischaemic attack (TIA)?
A mini stroke
Symptoms resolve completely after 24 hours
List 5 factors for stroke
2. High BP
3. Heart disease
4. Smoking - damages endothelium = collagen = releases platelets
How is blood supplied to the brain?
1. Carotid arteries
2. Vertebral arteries
3. Basilar artery
4. Communicating arteries
What is the role of the communicating arteries?
Used for cross-over flow when damage in one of the arteries
What is the role of the Circle of Willis
Anterior communicating artery allows temporary blood flow to areas of the brain where the blood supplied is blocked
What causes a thrombosis
When the atherosclerotic plaque ruptures
This interrupts blood supply to the neurons
Rapid death of brain tissues leads to loss of brain function
Starving of oxygen
Mainly due to thrombosis
List 2 causes of an ischemic stroke
What is an embolism?
Portion of a blood clot (embolus) can travel to the brain and stop the blood flow
Heart is the common source of embolisms