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Flashcards in Therapeutics Deck (4)
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1

Which drugs are P450 enzyme inducers

Carbamazepine
Rifampicin
bArbiturates
Phenytoin
St John's Wort

2

Which drugs are P450 enzyme inhibitors

Some certain silly compounds annoyingly inhibit enzymes, grrr

Sodium valproate
ciprofloxacin
sulphonamide
Cimetidine/omeprozole
Antifungals, amiodarone
Isoniazid
Erythromycin/clarithromycin
Grapefruit juice

3

Which drugs are affected by P450 metabolism

warfarin
COCP
theophylline
corticosteroids
tricyclics
pethidine
statins

4

Name some drugs with narrow therapeutic ranges

lithium
digoxin
gentamicin
warfarin
methotrexate
theophylline
phenytoin
insulin
ciclosporin