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PHARMA I > TETRACYCLINES > Flashcards

Flashcards in TETRACYCLINES Deck (7)
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1
Q

what are the examples?

bacteriostatic or bactericidal?

A

doxycycline
minocycline
tetracycline
tigecycline

bacteriostatic

2
Q

what is the MOA?

A

30S ribosomal subunit

3
Q

distribution?

A

bones
dentine
enamel
unerupted teeth

4
Q

tetracycline, doxycycline, minocycline has spectrum against?

A
staph (MRSA), strep
atypicals
rickettsia
spirochetes
plasmodium species
5
Q

tigecycline and eravacycline has spectrum against?

A
atypical 
enterococci (VRE)
staph (MRSA)
strep
GNRs

except pseudomas

6
Q

used for most importantly?

A

life threatening infections involving resistant bacteria

7
Q

ADRs and preg? *developmentally

A

avoid in preg (Cat D) and children under 8

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