Systemic Antiviral Agents Flashcards Preview

Pharmacology > Systemic Antiviral Agents > Flashcards

Flashcards in Systemic Antiviral Agents Deck (9)
Loading flashcards...
1
Q

Activation of ACV requires phosphorylation by Herpes specific thymidine kinase (TK)

A

T

2
Q

Acyclovir is a guanosine analog which is pregnancy category B

A

True

3
Q

Acyclovir inhibits viral DNA polymerase by serving as an obligate chain terminator in its triphosphorylated form

A

True

4
Q

PAST Q: Oral acyclovir urinary excretion is not affected by probenecid

A

False

5
Q

Past q

Acyclovir safe in pregnancy

A

True

6
Q

Past q

Acyclovir is inactivated by viral thymidine kinase

A

False

7
Q

Past q

Acyclovir is excreted mainly by the kidney

A

False

Roughly equal urine and faecal excretion

8
Q

Past q

Acyclovir is excreted mainly by the kidney

A

False

9
Q

Acyclovir has no hepatic microsomal metabolism

A

True