Sympathomimetics Flashcards Preview

RUSVM Pharmacology 2016 > Sympathomimetics > Flashcards

Flashcards in Sympathomimetics Deck (17)
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1
Q

Epinephrine - receptor and Uses?

A

Alpha-1, Alpha 2, Beta-1, beta-2 agonist – used in cardiac arrest, anaphylaxis, local vasoconstriction and topically for local hemorrhage

2
Q

Norepinephrine- receptor and uses?

A

Agonist alpha-1 Alpha-2 and beta-1 – causes vasoconstriction and increased afterload

3
Q

Dopamine – receptor and uses?

A

In low dose Dopamine agonist that causes vasodilation, medium low doses beta-1 agonist causes positive inotrope, medium high dose Beta-1 agonist causes increased heart rate and high-dose beta-1 agonist causes vasoconstriction

4
Q

Dobutamine- receptor and uses?

A

Same as dopamine – synthetic Beta-1 agonist with minor beta-2 and alpha-1 agonist causes the same effects as dopamine. Used more in large animals especially for acute heart failure

5
Q

Isoproterenol- receptor and uses?

A

Nonspecific beta agonist causes positive inotropic effect and increased blood flow and bronchodilation – not used in veterinary medicine because of the strong

6
Q

Phenylephrine - receptor and uses?

A

Direct acting alpha-1 agonist causing increased peripheral vascular resistance used to treat hypertension and cats and dogs

7
Q

Selective beta-2 agonists

A

Albuterol, salbutamol, clenbuterol, terbutaline, isoxsuprine

8
Q

Albuterol/ Salbutamol- receptor and uses?

A

Used in inhalers

9
Q

Clenbuterol- receptor and uses?

A

Used for equine dystocia because it causes uterine relaxation

10
Q

Terbutaline -receptor and uses?

A

Used in small animal for bronchodilation

11
Q

Isoxsuprine -receptor and uses?

A

Used for bovine dystocia

12
Q

Nonselective beta agonist Ractopamine and Zilpaterol -receptor and uses?

A

Beta 3 agonist used for increased carcass leanness, feed efficiency, and increased deposition of muscle

13
Q

Indirect acting sympathomimetics

A

Clomipramine- serotonin agonist
Doxepin- serotonin agonist- antihistamine
Monoamine oxidase inhibitor- Selegiline- inhibits the reuptake of norepinephrine and breakdown

14
Q

Direct and indirect acting sympathomimetics

A

Phenylpropanolamine

Ephedrine

15
Q

Phenylpropanolamine -receptor and uses?

A

Direct alpha-1 agonist used to treat urinary incontinence due to urethral sphincter are incompetence

16
Q

Ephedrine -receptor and uses?

A

Direct alpha-1 and beta agonist used as a CRO to maintain blood pressure under anesthesia causes increased blood pressure, cardiac stimulation and bronchodilation

17
Q

Direct Acting Catecholamines

A
Epinephrine
norepinephrine
dopamine
dobutamine
isoproterenol
Phenylephrine