STI/PID/PATH

Question 1

Most common viral STI

Answer 1

HPV

Question 2

Most common bacterial STI

Answer 2

chlamydia

Question 3

____ epithelium is more resistant to infection than _____ epithelium

Answer 3

squamous vs glandular

Question 4

_____ tests are the most common and recommended platforms for detection of common STIs

Answer 4

nucleic acid amplification tests –> chlamydia, gonorrhea, herpes, trichomonas, hpv

Question 5

Serologic tests are commonly used for which common STIs?

Answer 5

syphilis, hep B, hep C

Question 6

____ typically infects the glandular epithelia of the cervix resulting in purulent discharge.

Answer 6

Gonorrhea

Question 7

Gonorrhea is typically symptomatic in M/F

Answer 7

M (though sometimes increase in vaginal discharge without itching)

Question 8

Growth requirements for gonorrhea

Answer 8

thayer martin/chocolate agar + humid atmosphere with CO2

Question 9

What is the risk of contracting gonorrhea after single exposure to infected man?

Answer 9

50% risk for women

Question 10

What is the risk of contracting gonorrhea after single exposure to infected woman?

Answer 10

20% risk for men

Question 11

Best way to ID gonorrhea

Answer 11

urine test (gram stain only sensitive if symptomatic)

Question 12

Intracellular parasite with small gram-negative bacilli

Answer 12

chlamydia

Question 13

Why is chlamydia not as acute as gonorrhea

Answer 13

intracellular infection leads to cellular immune response

Question 14

M/F have higher rate of chlamydia than M/F

Answer 14

F > M

Question 15

Perinatal transmission of chlamydia contributes to neonatal ____ in 30-50% of exposed babies.

Answer 15

conjunctivitis

Question 16

T/F gonorrhea and chlamydia often cause vaginitis

Answer 16

F –> squamous epithelium is resistant

Question 17

____ produces peroxides in the vagina contributing to infection resistance.

Answer 17

lactobacilli

Question 18

PID

Answer 18

upper tract infection involving endometrium, fallopian tubes, or ovary

Question 19

____ and ____ are the only true causes of PID

Answer 19

gonorrhea and chlamydia

Question 20

T/F upper tract infections need more broad spectrum Abs than lower tract infections.

Answer 20

T

Question 21

adnexa

Answer 21

that area of the ovarian tube adjacent to the uterus

Question 22

complications of acute PID

Answer 22

infertility from scarring/hydrosalpinx, ectopic pregnancy, chronic pelvic pain, tubo-ovarian abscess/peritonitis

Question 23

Interstitial salpingitis

Answer 23

consequence of patent fimbrial end with scarring within the tube

Question 24

Tubo-ovarian abscess

Answer 24

if fallopian tube is inflamed and infection spreads to ovary, pus simply fills the interstitial space

Question 25

Pyosalpinx

Answer 25

occlusion of the fimbriated end prevents release of tubal content –> exudate is absorbed and forms a hydrosalpinx after the acute phase

Question 26

Pathologic definition of pid

Answer 26

chronic salpingitis with involvement of surrounding structures including ovary and parametrium

Question 27

IUD and PID relationship

Answer 27

no increased rate of PID or ectopic pregancy

Question 28

Historically ____ infection was associated with IUDs, probably due to coinfection with asymptomatic gonorrhea or chlamydia.

Answer 28

actinomyces israelii

Question 29

Tubal abortion of ectopic pregnancy

Answer 29

expelled from fimbrial end of tube

Question 30

Tubal hemorrhage due to ectopic pregnancy

Answer 30

decidual change is focal and poorly developed –>cannot buffer trophoblastic invasion of vessels

Question 31

Tubal rupture in ectopic pregnancy

Answer 31

50% of tubal pregnancies –> acute onset, intraabdominal hemorrhage, acute abdominal pain

Question 32

T/F new IUDS are not associated with increased risk of PID and ectopic pregnancy

Answer 32

T

Question 33

T/F ectopic pregnancy is a potential sequelae of pid due to post-inflammatory damage to fallopian tubes

Answer 33

T