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Flashcards in Spinal Cord Deck (66)
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1

What is the neural tube derived from?

Ectoderm

2

What substance is secreted by the notocord that converts it to the neural tube?

Sonic Hedgehog

3

What nutrient affects neural tube development?

Folic acid

4

What structure precedes the neural tube?

The neural plate

5

Describe neural tube formation

A groove forms in the neural plate
The inner walls form into inner + intermediate mantle and outer marginal layers
The mantle layer forms dorsal (alar) and ventral (basal) plates
Tissues at the sides of the tube form the neural crest cells

6

What part of the neural tube forms sensory neurons in the dorsal horn of the grey matter?

Alar plate

7

What part of the neural tube forms motor neurons in the ventral horn of the grey matter?

Basal plate

8

What does the innermost layer of the neural tube develop into?

Ependymal cells

9

What do the neural crest cells give rise to?

DRG, adrenal medulla, melanocytes, enteric ganglia, schwann cells, sympathetic ganglia

10

What CNS cell is mesodermally derived?

Microglia

11

Where does the spinal cord begin and end?

Foramen magnum and L1/L2 in an adult

12

What are the 2 enlargements of the cord?

Cervical and lumbosacral

13

Where is the cervical enlargement largest?

C6

14

What is the dilated end of the spinal cord?

Conus medullaris

15

What are nerves that exit the end of the spinal cord called?

Cauda equina

16

What is structures of the cord are derived from pia mater?

Dentate ligaments, filum terminale

17

What is the function of the dentate ligaments?

They anchor the cord to the dura

18

Where is the filum terminale internum?

From conus medullaris to the end of the dural sac

19

Where is the end of the dural sac?

S2

20

Where is the filum terminale externum?

anchored to the coccyx, continuous witht he coccygeal ligament

21

What are fasciculi?

Fast conducting white matter that ascend and descend

22

What spinal tracts are associated with 2 point discrimination, vibration, and joint position sense?

Cuneatus and gracilis tracts

23

Where do cuneatus and gracillis cross

In the medulla

24

What is the destination of a third order neuron in tracts gracilis and cuneatus?

VPL of the thalamus

25

What do cuneatus and gracilis tracts differ in control of?

Which set of limbs

26

Between cuneatus and gracilis, which tract controls upper limbs?

Tracts gracilis

27

What two spinal tracts are collectively known as the "anterolateral" system?

Ventral and lateral spinothalamic tracts

28

What type of information is carried by the spinothalamic tracts?

Crude pressure, nociception, and thermoreceptors

29

Where do the spinothalamic tracts cross?

In the cord

30

Which crosses quicker the ventral or lateral spinothalamic tract?

Lateral