Flashcards in Small Animal Nursing Deck (537)
Packed RBCs: what is extracted, how long can you store it, how can you take care of it after it is harvested, treatment for?
2) Storage up to 37 days, refrigerated(Storage depends on anticoagulant used)
3)the packed RBCs should be reconstituted in a nutrient rich solution to maintain cells in a healthier environment
Stored Plasma: harvested from, provides what, how long can it be stored, treatment for?
1) By product of harvesting packed RBCs from stored whole blood
2) provides only plasma proteins
3) Can be stored up to 21 days under refrigeration at 1- 6 C depending on the anticoagulant used or 5 years at –20 C
4) animals with hypoproteinemia
Cryoprecipitate: harvested from, what is extracted, used to treat?
1)Harvested from fresh frozen plasma that has been thawed a 1-6 C until it is slushy consistency
2) The slurry plasma is then centrifuged at 5000 G at 4 C for 7 minutes. The plasma is extracted leaving behind in the bag a white, foamy precipitate (50-100ml). Can be frozen at –20 for up to a year from the date of collection
3) VWD, hemophilia A and hypo- fibrinogenemia
Platelet Rich Plasma: harvested from, stored for how long, treatment of?
1) Harvested by centrifuging fresh whole blood at 1200 G at 22 C for 2 minutes
2) Then it is allowed to sit undisturbed for 30 minutes, then the platelet rich plasma is removed. Stored at room temperature for up to 5 days
3) low platelet numbers, platelet dysfunction
Dogs typed _____ are considered universal donors
negative for DEA 1.1 (doesn't have antigen)
____ synthetic bovine hemoglobin, for anemia, only 1 time use but can cause icterus and discolored urine
T/F Transfusions should gradually warm; allowed to sit at room temperature for 30 minutes. Frozen product should be warmed in a 37 C water bath
T/F There are thirteen (19 in new publications) canine blood groups. DEA 1.1, DEA 2, DEA 3, etc
_____ is the most powerful stimulus for a reaction
_____ and ___ are less pronounced but can cause problems.
DEA 1.1, DEA 1.2 and 7
T/F Clinically significant reactions do not occur on initial transfusions.
DEA ___, ___, and ____ antigens can develop transfusion reactions from mismatched blood 4-14 days post transfusion
-DEA 1.1, DEA 1.2 and DEA 7
What does DEA stand for?
Dog Erythrocyte Antigen
T/F If multiple transfusions are needed the blood needs to be crossed matched to detect donor (recipient incompatibility)
What are the 3 feline blood groups? Which is the most common and most rare and purebred?
A (most common in USA), B (purebred), AB (rare)
T/F Cats have a universal donor.
What drug stimulates bone marrow?
Cats are prone to transfusion reactions, so what should you do before administering a transfusion?
All cats should be type prior to receiving a transfusion
T/F AB type cats can be transfused with A type blood generally without any significant problems.
Also known as hemolytic icterus, is a disease found in kittens and foals. It occurs when the mother has antibodies against the blood type of the newborn. In cats, the antibodies are already present in the queen's blood before parturition. The blood group antigens are similar in structure to the antigen of a common bacteria in the gut of cats leading to antibody formation.
Most cats need to be ____ in order to donate blood.
sedated (only indoor cats used)
Canine donors donate ___ml/kg every 3 weeks, feline donors donate ___ml/kg every 3 weeks
T/FOnce a blood container has been entered the product should be used within 24 hours.
true (whole blood should be mixed periodically)
Solutions that maintain blood cell viability during storage (anticoagulants)
-Sodium Citrate 3.8%
Temperature cannot vary more than 2 C and the blood cannot be left un-refrigerated for more than ___ minutes
1) Rates should not exceed ___ml/kg/hr
2) Cardiovascular compromise cannot tolerate infusion rates above __ml/kg/hr
3) Initial infusion should always be administered slowly for the first ____minutes while monitoring signs for acute reaction
4) Administering one unit of blood should not take longer than __ hours
5) Some Doctors will give a injection of Benadryl before the transfusion, why?
3) 15 –20 mins
4) 4 hours
5) in case of a reaction
What is the first sign of a transfusion reaction? Other signs?
-*rise in temperature (parameters should be checked every 30 mins)