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Flashcards in skin and soft tissue infections Deck (13)
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1

describe staph aureus and it's virulence factor

gram positive, grape like clusters. panton valentine leukocidin toxin - punches holes in epithelium - marcophages migrate to here - these are then attacked and killed - tissue necrosis

2

give examples of an infection caused by staph aureus

puss forming - impetigo, boils, surgical wound infections, endocarditis
toxin producing - endotoxin - toxic shock syndrome

3

describe strep pyrogenes and give an example of an infection caused by it

gram positive cocci chains. superantigen - body over reacts to antigen, host response causes destruction. toxic shock syndrome, cellulitis

4

describe streptococcus anginosous group and give an example of infection

gram positive chains, cytotoxin - intermedialysin, dental absess

5

describe anaerobes and give an example of an infection

gram positive bacilli, lecithinase - lecthin is a fatty acid between membranes - attacked to allow spread of disease. necrotising fascitis

6

describe candida albicans and give an example of infection

fungi - yeast cells and hyphae. phospholipase - breaks down phospholipids in cell membranes. candidiasis erythamtous

7

give an example of an infection in the epidermis

impetigo - staph aureus

8

give an example of an infection in the dermis

facial erysiplas - group a streptococcus

9

give an example of an infection in the hair follicles

folliculitis - inflammation - staph aureus
boils - staph aureus deep seated, bottom of follicle, if many hair follicles involved - carbuncles

10

give an example of an infection in subcutaneous fat

cellulitis - strep pyrogenes

11

give an example of an infection in the fascia

nectrotising fascitis - anaerobes, staph aureus and strep pyrogenes

12

give an example of an infection in the muscle

myonecrosis - gas gangrene and clostridium perfringes

13

how are infections treated

diagnosis - need to know what is causing infection for treatment
surgical debridement - removal of tissue necrosis and puss - needs to be done but wont get to centre
antibiotics - kills microbes, can remove all bacteria but only if been debrided