Singh 3 Flashcards

1
Q

The Spinal Cord:

Length?

Extent (both organ and skeletal)

Define the “conus medullaris”

A

The Spinal Cord:

Length: 43-45 cm

Extent: from base of medulla to the conus medullaris (end of spinal chord)

OR from a skeletal view from the foramen magnum to the interspace between L1-L2 vertebrae in the adult

Conus Medullaris: located at the caudal tip of the spinal cord, located in L3 in kids and L1 in adults

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2
Q

The Spinal Cord

  • Define the following terms:

Filum terminale

Cauda Equina

Central Canal

A

Spinal Cord:

Filum Terminale: extends from the tip of the conus and attaches to the distal dural sac (consists of pia and glial fibers and often contains a vein)

Cauda Equina: the dorsal and ventral spinal rootlets of the lumbar and sacral spinal nerves

Central Canal: lined with ependymal cells and filled with CSF

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3
Q

The spinal roots:
Dorsal roots carry ________ fibers with cell bodies in ____

Ventral roots carry ________ fibers with cell bodies in _______

A

The spinal roots:

Dorsal roots carry afferent fibers with cell bodies in DRG

Ventral roots carry efferent fibers with cell bodies in ventral gray matter

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4
Q

Remember for the spinal cord

DORSAL means ____

Ventral means _____

A

DORSAL for the spinal cord is posterior (SENSORY)

Ventral means anterior/in front (MOTOR)

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5
Q

Pattern of Spinal Nerve Emergence:

In the cervical cord, nerve roots exit _____

In the lower cord, nerve roots exit ______

A

Pattern of Spinal Nerve Emergence:

In the cervical cord, nerve roots exit above vertebrae

In the lower cord, nerve roots exit below vertebrae

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6
Q

Functions of the spinal cord:

1.

2.

3.

4.

A

Functions of the Spinal Cord:

  1. Conduit for the transmission of crucial nerve impulses (information) connecting the brain with most of the body
  2. Segmental reflexes
  3. Control of motor activity
  4. Modulation of sensory phenomena, especially pain transmission, and proprioception
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7
Q

Basic Structure of the Spinal Cord:

Gray Matter includes the:

1.

2.

3.

White matter includes:

1.

2.

3

A

Gray matter (contains cell bodies, is middle of chord)

  1. ventral horn
  2. dorsal horn
  3. intermediolateral gray column (ANS)

White Matter: myelinated fibers, axons

  1. Dorsal columns
  2. Lateral columns
  3. Anterior/ventral columns
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8
Q

Explain the following terms and show where they are in the image below:

Posterior Lateral Sulcus

Anterior lateral Sulcus

Anterior/ventral median fissure

A

Posterior Lateral Sulcus: dorsal root entry zone

Anterior Lateral Sulcus: ventral root exit zone

Anterior/ventral median fissure: contains the sulcal branch of the anterior spinal artery (aka the cord’s intrinsic arterial blood supply)

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9
Q

Define the following terms:

Posterior/dorsal median sulcus

Posterior/dorsal intermediate sulcus

A

Posterior/dorsal median sulcus: seperates the right and left dorsal funiculi

Posterior/dorsal intermediate sulcus: present only in segments above T6

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10
Q

Explain the differences in the gray and white matter in the spinal cord cross sections (differences between cervical, thoracic, and lumbar)

A

Notable, the gray matter is the smallest in the thoracic region

The white matter is the largest in the cervical region

and the gray matter is the biggest in the lumbar region

A key point here is that the dorsal/ventral horn appears larger in segments of the spinal cord that serve extremities

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11
Q

Gray Matter of the Cord:

Organization: related to degree of _______

Where are the enlargements?

Where does the sympathetic neurons lie?

A

Gray matter of the cord:

Organization: related to degree of innervation supplied by the segment

C4-T1: cervical enlargement:

  • Brachial plexus
  • Large posterior and ventral gray horns

L1-S2 lumbar enlargement:

  • Lumbrosacral plexus
  • Large posterior and ventral gray horns

Sympathetic neurons: Intermediolateral cell column

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12
Q

White Matter Organization:

Expplain the Posterior/Dorsal Column

List important functions of the dorsal column

A

Posterior (dorsal) column:

Sensory pathways only

Fasc. gracilis and fasc. cuneatus (aka the dorsal columns that dorm the DCML sensory pathway)

Proprioception, epicritic sensation (two point discriminative touch and vibratory sensation) are carried by pathways of the posterior columns

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13
Q

White Matter Organization:

Explain the lateral columns

A

White Matter Organization:

Lateral Column (or funiculus):

  • SENSORY (lateral spinothalamic tract)

and MOTOR (lateral corticospinal tract)

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14
Q

White Matter Organization:

Explain the Anterior/Ventral Column or funiculus

A

Anterior/Ventral Column

MOTOR pathways primarily (ventral corticospinal)

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15
Q

Explain what the following ascending pathways are related to:

Fasiculus Gracilis (DCML)

Faciculus Cunneatus (DCML)

Lateral and ventral spinothalamic tracts

A

Fasiculus Gracilis (think graceful legs…. LEGS)

Faciculus Cunneatus…. arms

Lateral and ventral spinothalamic tract: pain and temperature sensation

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16
Q

Explain the following spinal cord tracts:

Ascending:

Faciculus Gracilis & Faciculus Cuneatus

A

Remember, the fasiculus gracilis and fasciculus cuneatus make up the DCML pathways

THINK concious proprioception

Leg nerve enters fasiculus gracilis (arm enters cuneatus)

The axons of these neurons ascend uncrossed in the posterior finiculi to the nucleuses located in the medulla oblongata

they then cross over to the primary somatosensory cortex in the brain

17
Q

Explain the lateral spinothalamic tract

A

Lateral Spinothalamic: think pain and temperature

these neurons cross the middle region (region of decussation) within the spinal cord

18
Q

Explain the anterior spinothalamic tract

A

Anterior spinothalamic tract: think touch and pressure

19
Q

What is an important function of Lissauer’s tract (aka posterolateral tract)?

A

Lissauer’s Tract (aka the posterior lateral tract) carries information related to location, intensity, and quality of pain

20
Q

Explain looking at a cross-section of the spinal cord, where the following areas that are in charge of these functions lie:

Voluntary Motion

Proprioception, Pain, Temp, Pressure

Proprioception, deep touch, vibration

A
21
Q

Explain the corticospinal tract

A
22
Q

What is the babinski sign?

Presence of a babinski sign is evidence of what?

A

Normally, when you graze an object down your foot you are supposed to curl your toes and point downward

The babinski sign is when you extend your feet upward

It is a sign of an issue with your corticospinal tract

Infants have this because their corticospinal tract (which is also in charge of fine motor control) is not fully developed

23
Q

What are some signs of upper motor neuron defecits?

1.

2.

3.

4.

5.

A

Upper motor neuron defecits:

Spastic paralysis

hyper-reflexia

little to no muscle atrophy

no fasiculations

presence of babinski sign

24
Q

What are some signs of lower motor neuron defecits?

1.

2.

3.

4.

5.

A

Lower motor neuron defecits:

Flaccid paralysis

Hypo-reflexia

significant muscle atropy

fasiculations present

no babinski sign

25
Q

Gray Matter of the Cord:

Rexed’s Laminations:

Explain Lamina 1-5

Lamina 8-9

and then the ones in between

A

Gray Matter:

Lamina I-V: contain neurons in the dorsal grey horn that receive primarily sensory input

Lamina VIII-IX: contaian ventral horn motor neurons

The ones in between (6 and 7) contain things for the autonomic nervous system

26
Q

The ANS is part of the CNS although it is controlled by the CNS:

The ANS maintains homeostasis and responds to threats

Symp: Fight or flight

PSNS: Rest and digest

A

Innervations are LARGELY sympathetic

27
Q
A