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Developmental Biology > Signalling > Flashcards

Flashcards in Signalling Deck (5)
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1
Q

Define juxtacrine signalling

A

Contact between inducing and responding cells

2
Q

Define paracrine signalling

A

Diffusion of inducers from one cell to another

3
Q

Define autocrine signalling

A

The same cell is both inducer and responder

4
Q

Define Matrix signalling

A

The matrix of one cell close to another sends the paracrine signal

5
Q

The five key steps of a signal transduction pathway

A
  1. Receptor activation
  2. Transcription factor activation
  3. Nuclear localization
  4. Chromatin decompaction
  5. Coupled initiation and 5’ capping