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1

Result of excessive mast cell degranulation mediated by IgE antibodies in response to antigen

Anaphylactic Shock

2

In _________ shock, mast cells release vasodilatory mediators resulting in severe ______

anaphylactic; hypotension

3

Name 4 causes of anaphylactic shock

Antibiotic therapy (in particular β-lactams), peanuts and tree nuts, insect stings, and snake bites

4

Urticaria
Bronchoconstriction
symptoms of ________ shock

anaphylactic

5

Stridor
Angioedema
symptoms of ______ shock

anaphylactic

6

Wheezing
Itching
symptoms of ______ shock

anaphylactic

7

Treatment includes maintenance of airway patency, use of epinephrine, bronchodilators_________ shock

anaphylactic

8

Treatment includes antihistamines, vasopressors, and IV fluids

anaphylactic

9

Results from loss of sympathetic activation of arteriolar smooth muscle

Neurogenic shock

10

Neurogenic shock causes include ______ depression (brain injury, drug overdose) or lesions of ______ nerve fibers (spinal cord injury)

medullary; sympathetic

11

Treatment includes vasopressors, fluids, elevation of the legs

Neurogenic shock

12

Treatment includes slow position changes, and the use of pressure stockings on the legs

Neurogenic shock

13

Results from severe systemic inflammatory response to infection

Septic Shock

14

In ________ shock, Body’s response to infection or other insults results in systemic signs and symptoms of widespread inflammation: leading to ______

septic; SIRS

15

3 common causes of septic shock

Gram-negative and gram-positive bacteria, fungal infections

16

Endotoxins in bacterial cell walls stimulate massive immune system activation

Gram negative shock

17

Characterized by release of immune mediators resulting in widespread inflammation

septic shock

18

______ cascade, _______ system, and _ system are activated in septic shock

clotting, complement, kinin

19

In _______ shock, widespread inflammation leads to profound peripheral vasodilation with ____, maldistribution of blood flow with cellular _____, and increased capillary permeability with _____ formation

septic; hypotension; hypoxia; edema

20

Initially characterized by high CO due to sympathetic activation of the heart and warm extremities

septic shock

21

Even though CO is high, cellular ______ is present in _____ shock

hypoxia; septic shock

22

Reduced cellular oxygen utilization is manifested as high ____ in septic shock

SvO2

23

______ can deteriorate to a hypodynamic phase, causing decreased CO and organ _____

septic shock; ischemia

24

Therapy aimed at improving the distribution of blood flow and managing infection with antibiotics

Septic Shock

25

Administration of fluids and drugs to improve cardiac and vascular performance to improve distribution of blood flow

Septic Shock

26

Which of the following types of shock is septic shock?

Cardiogenic shock
Distributive shock
Obstructive shock
Hypovolemic shock

Distributive

27

Used to guide management of cardiac preload, afterload, and contractility to optimize CO and minimize workload

Hemodynamic Monitoring

28

Helpful for assessing CO, volume status, and oxygen delivery and consumption

Hemodynamic Monitoring

29

Hemodynamic Monitoring monitors_____(3)

Right atrial pressure, pulmonary artery pressure, and left atrial pressure

30

Oxygen delivery

DO2