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NBCE Part 1 > Set 25 Micro Diseases > Flashcards

Set 25 Micro Diseases Flashcards

1
Q

What id DiGeorge syndrome?

A

thymic tissue missing (bubble boy), no T cells

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2
Q

What is severe combined immunodeficiency syndrome?

A

No B or T cells, worse than bubble boy

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3
Q

What is Kaposi’s sarcoma associated with?

A

AIDS/HIV-1

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4
Q

What does Kaposi’s sarcoma target?

A

helper T cells, macrophages, and dendritic cells

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5
Q

Which polio vaccine is “dead”?

A

salk

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6
Q

Which polio vaccine is “alive”?

A

sabin

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7
Q

How does a Salk vaccine work?

A

looks like polio, generates memory helper T cells and B cells, but not memory killer T cells

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8
Q

What is an attenuated vaccine?

A

weakened form of microbe

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9
Q

Most vaccines are:

A

attenuated

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10
Q

Why are attenuated vaccines “better”?

A

produce memory killer T cells

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11
Q

What is the downside to carrier vaccines?

A

expensive

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12
Q

What is a carrier vaccine?

A

genetically engineered, doesn’t cause disease

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13
Q

What is active immunity?

A

that caused by live or killed viruses

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14
Q

What is passive immunity?

A

occurs naturally from mother’s milk

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15
Q

What is passive-active immunity?

A

both immunoglobulins and vaccine

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16
Q

What is serology?

A

study and diagnostic use antigen-antibody interactions in blood serum

17
Q

What are precipitates?

A

antigen-antibody mixed, insoluble, huge complexes formed

18
Q

What is immunodiffusion?

A

used to test for fungal antigens

19
Q

What is immunoelectrophoresis?

A

seperates molecule, looks for particular class of antibodies, used for Borella burgdorferi (lyme disease)

20
Q

What is viral neutralization?

A

sensitive and specific, used to ascertain whether patient exposed to a particular virus

21
Q

What is viral hemagglutination inhibition test?

A

clumps RBCs, not antibody-antigen reaction, used for influenza

22
Q

What is the fluorescent antibody test?

A

dye used, example TB

23
Q

What are ELISAs?

A

enzyme linked immunosorbent assay, enzyme labels antibodies for HIV

24
Q

What is western blot?

A

verifies presence of antibodies against HIV (AIDS confirmation hearing)

25
Q

What are immunofiltration assays?

A

rapid ELISAs

26
Q

What is agglutination?

A

blood typing, pregnancy testing

27
Q

What can be diagnosed by agglutination?

A

salmonellosis, brucellosis, gonorrhea, rickettsial, mycoplasma, yeast, typhoid fever, meningitis

28
Q

What is the primary dye for bacteria?

A

crystal violet

29
Q

Positive:

A

purple

30
Q

Negative:

A

pink

NBCE Part 1 (40 decks)

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