Set 24 Micro Immuno Flashcards

1
Q

What are the phagocytic cells of the immune system?

A

neutrophils, monocytes, and macrophages

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2
Q

What are the inflammatory mediator cells?

A

basophils, mast cells, eosinophils

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3
Q

What is the function of cytokines?

A

activate helper and cytotoxic T cells, kill pathogen or tumor cells

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4
Q

What is the function of NK cells?

A

can inactivate pathogens

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5
Q

What is the function of Killer T cells?

A

kill virus-infected cells by triggering target cell suicide

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6
Q

What is the function of Helper T cells?

A

help in antigen recognition and regulation

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7
Q

What do helper T cells secrete?

A

cytokines

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8
Q

What is an antigen?

A

target of antibodies and T cells

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9
Q

What is an epitope?

A

part of an antigen recognized by immune system

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10
Q

What is the function of CD4/Class I cells?

A

informs killer T cells of what is going on inside cells

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11
Q

What is the function of CD8/Class II cells?

A

informs helper T cells of problems outside cells

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12
Q

What is the function of an antibody?

A

tags an invader

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13
Q

What is Type I hypersensitivity?

A

immediate hypersensitivty (peanut, venom, penicilin) (outside in)

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14
Q

Which cells function in Type I hypersensitivity?

A

IgE, mast cells, basophils, allergic

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15
Q

Examples of Type I hypersensitivity:

A

anaphylaxis, hay fever, and asthma

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16
Q

What is Type II hypersensitivity?

A

antibody mediated (inside in)

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17
Q

Which cells function in Type II hypersensitivity?

A

IgG and IgM cause cell lysis

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18
Q

Examples of Type II hypersensitivity:

A

blood group incompatibility, pernicious anemia, myasthenia gravis

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19
Q

What is Type III hypersensitivity?

A

immune complex mediated (inside in)

20
Q

Which cells function in Type III hypersensitivity?

A

IgG, antibody mediated inflammation, and some autoimmune

21
Q

Examples of Type III hypersensitivity:

A

SLE, RA, serum sickness and rheumatic fever

22
Q

What is Type IV hypersensitivity?

A

T cell mediated (outside in)

23
Q

Examples of Type IV hypersensitivity:

A

infections, dermatitis, and graft rejections

24
Q

When did SARS outbreak in China?

A

2002

25
Q

When did bird flu outbreak in Asia?

A

2003

26
Q

What is the most common food borne disease?

A

norovirus

27
Q

What is the second most common food borne disease?

A

salmonella

28
Q

How many new cases of TB?

A

8.8 mil

29
Q

How many deaths from TB?

A

1.4 mil

30
Q

What shape are bacilli?

A

rod shaped

31
Q

What shape are cocci?

A

spherical

32
Q

What shape are spirochetes?

A

spinal

33
Q

What shape are spirilla?

A

spring

34
Q

What is mutualism?

A

both benefit

35
Q

What causes hay fever?

A

proteins from mold or plant spores

36
Q

What causes asthma?

A

dust mites, cockroaches, rodents, and household pets

37
Q

What is the process of asthma?

A

mast cells degranulate, histamine and other chemicals, IgE live 1 day, but weeks if attached to mast cells, basophils attach to IgE, and eosinophils have a chronic allergic reaction

38
Q

What is Canale-Smith syndrome?

A

self reactive lymphocytes repeatedly stimulated, swollen lymph nodes

39
Q

What is insulin-dependent diabetes mellitus?

A

organ specific immune disease - B cells target

40
Q

What is myesthenia gravis?

A

self-reactive antibodies bind to ACh receptors

41
Q

What is MS?

A

multiple sclerosis, CNS, self reactive T cells, myelin sheaths destroyed

42
Q

What is the course of MS?

A

macrophages recruited by cytokines secreted by T cells, activated T cells can cross BBB

43
Q

What is rheumatoid arthritis?

A

chronic joint inflammation

44
Q

What is the course of RA?

A

IgM or IgG antibody activates macrophages, ^ inflammation

45
Q

What is Lupus erythematosus?

A

red face rash, malar butterfly, inflammation of lungs, arthritis, kidney damage, hair loss, paralysis, and convultions

46
Q

What causes Lupus Erythematosus?

A

breakdown of B and T cells that make IgG