Session 8: Muscular System Flashcards

1
Q

What is the sarcolemma?

A

The outside membrane of a muscle cell.

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2
Q

What is the sarcoplasm?

A

The cytoplasm of a muscle cell.

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3
Q

Name the three types of muscle.

A
  1. Smooth
  2. Cardiac
  3. Skeletal
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4
Q

Describe skeletal muscle.

A
  • striated
  • multi nuclei
  • peripheral nuclei
  • fascicle bundles
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5
Q

Describe cardiac muscle.

A
  • striated
  • branched
  • 1-2 central nuclei
  • intercalated discs
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6
Q

Describe smooth muscle.

A
  • not striated
  • fusiform shape
  • no T tubules
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7
Q

What are the three layers within skeletal muscle? (Inside out)

A
  1. Endomysium
  2. Perimysium
  3. Epimysium
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8
Q

What is atrophy?

A

A loss of muscle mass as destruction of muscle cells is greater than muscle cell replacement.

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9
Q

What is hypertrophy?

A

A gain of muscle mass as destruction of muscle cells is less than muscle cell replacement. (Often see in body builders)

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10
Q

What diagnostic tool is used with patients with cardiac ischaemia?

A

Troponin assay

However quantity is not proportional to the degree of damage

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11
Q

What enzyme is released into the blood when cardiac muscle is damaged?

A

CK- creatine kinase

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12
Q

What can cause an increase in Creatine Kinase?

A
  • vigorous physical activity
  • fall (especially in the elderly)
  • muscular dystrophy
  • acute kidney injury
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13
Q

What type of muscle has a triad in its structure?

A

Skeletal

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14
Q

What type of muscle has a diad in its structure?

A

Cardiac Muscle

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15
Q

What is cell hypertrophy?

A

Increase in cell size.

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16
Q

What is cell hyperplasia?

A

Increase in cell number.

17
Q

What is AMP?

A

28 aa peptide that is released by atrial myocytes when atrial distention occurs (elevated blood volume)

18
Q

What peptides are used as a diagnostic marker for heart failure?

A

BNP and ANP

19
Q

How does smooth muscle repair itself?

A

Undergoes mitosis

20
Q

How does skeletal muscle repair itself?

A

Regenerates by mitotic activity of satellite cells

21
Q

How does cardiac muscle repair itself?

A

It can’t lol

Fibroblasts invade, divide and lay down scar tissue