S4) Case-Control Study Design Flashcards Preview

(LUSUMA) Introduction to Population Science > S4) Case-Control Study Design > Flashcards

Flashcards in S4) Case-Control Study Design Deck (9)
Loading flashcards...
1
Q

How does one conduct a case-control study?

A
  • Identify a group of cases
  • Identify a suitable group of non-cases (controls)
  • Ascertain previous exposure status of everyone
  • Compare level of exposure in cases and controls
2
Q

Identify 4 benefits of case-control studies

A
  • Quick
  • Cheap
  • Require less detailed information
  • Used for all outcomes (selected on the basis of having the outcome or not)
3
Q

How does one analyse a case-control study?

A
4
Q

How does one calculate the error factor for a case control study?

A
5
Q

How does one calculate the 95% confidence interval for a case-control study?

A

Confidence interval = (OR/ef) to (OR x ef)

6
Q

What is the ratio of controls to cases?

A

Usually, 4 - 6 x as many controls as there are cases because precision of an OR is affected by the number of controls and also cases

7
Q

Identify 3 primary issues for case-control studies

A
  • Selection bias
  • Information bias
  • Confounding
8
Q

How can one deal with selection bias?

A
  • Cases selected should be representative of all cases
  • Controls selected should be representative of the population from which the cases came
9
Q

How can one deal with confounding?

A
  • Minimise confounding in selection (matching)
  • Adjust for confounding in analysis (adjusting)