Psychopath lecture 3 Flashcards

1
Q

In stress what happens to the sympathetic activity?

A

-Increased

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2
Q

What are the normal types of anxiety disorders?

A

-Chronic, mild anxiety

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3
Q

What are the symptoms of chronic mild anxiety?

A
  • Tense

- Irritable

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4
Q

What is the treatment for chronic mild anxiety?

A

-Do things that help you relax

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5
Q

If you have chronic moderately sever anxiety how long has it been going on for?

A

-Longer than 6 months

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6
Q

What are the symptoms for chronic moderately severe anxiety?

A
  • Poor concentration

- No obvious reason

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7
Q

What are the treatment options for chronic moderately sever anxiety?

A

-Use anxiolytics/sedatives

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8
Q

What are the typical drugs used for anxiety?

A

-Benzodiazepines

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9
Q

What do Benzodiazepines act on?

A

-Agonists for BDZ receptors (decrease activity)

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10
Q

What does an agonist on BDZ receptors do?

A

-It is an allosteric modulator of GABA A receptors

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11
Q

What type of effect does Benzodiazepines have respiration?

A

-Has Little effect

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12
Q

What are the most popular CNS depressants?

A

-Benzodiazepines

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13
Q

What are the therapeutic action of Benzodiazepines?

A
  • Anxiolytics
  • Treat seizures
  • Alcohol withdrawal
  • Insomnia (hypnotic short acting)
  • Muscle relaxation
  • Often used a couple hours before surgical dental procedures
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14
Q

What are the adverse effects of Benzodiazepines?

A
  • Tolerance
  • Can cause addiction and withdrawal
  • Interacts synergistically with other depressants
  • Drowsiness
  • Motor impairment
  • Don’t use in a pt with major depression
  • Decrease cognition
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15
Q

What are the two sedative benzodiazepines?

A
  • Diazepam (Valium)

- Alprazolam (Xanax)

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16
Q

What is the half life of Diazepam (Valium)?

A

-20-100 hrs

17
Q

What is the half life of Alprazolam (Xanax)?

A

-6-12 hrs

18
Q

What are the two hypnotic benzodiazepines?

A
  • Lorazepam (Ativan)

- Triazolam (Halcion)

19
Q

What is the half life of Triazolam?

A
  • 2 hrs
20
Q

What is the half life of Lorazepam?

A

-6 hrs

21
Q

What is a benzo like sleep aid?

A

-Zolpidem (Ambien)

22
Q

What is the half life of zolpidem (Ambien)?

A

-2 hrs

23
Q

What do Barbiturates do?

A

-Enhance GABA

24
Q

What is a barbiturate that is used for short term anesthesia?

A

-Pentobarbital

25
Q

What is a barbiturates used for long-term seizures?

A

-Phenobarbital

26
Q

What do barbiturates have major interactions with?

A
  • Liver

- Many drugs

27
Q

What is Propofol (Barbiturate) used for?

A

-General anesthesia

28
Q

What is a non sedative anxiolytic?

A

-Buspirone (BuSpar)

29
Q

What are the side effects of Buspirone (BuSpar)?

A
  • Irregular heart beat

- Interacts with MAOi or antiseizure medicines

30
Q

What are indications to use Buspirone (BuSpar)?

A
  • anxiety or tension associated with everyday stress

- If a person has co-existing depression with anxiety

31
Q

What symptoms do you see with Severe acute anxiety panic attacks?

A

-Increased sympathetic
-End up in the hospital because it seems like a Heart attack
-

32
Q

What are panic attacks treated with?

A
  • Paxil

- Venlafaxin

33
Q

What is Paxil?

A

-An SSRI used to treat panic attacks

34
Q

What is Venlafaxin?

A

-An antidepressant with mixed effects to treat panic attacks

35
Q

What are phobic disorders?

A

-Irrational fears

36
Q

What is agoraphobia?

A

-Fear of space

37
Q

What drug do you use to treat phobic disorders?

A

-SSRIs such as Zoloft