prostate cancer Flashcards

1
Q

define prostate cancer?

A

primary malignant neoplasm of the prostate gland

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2
Q

what are the risk factors of prostate cancer?

A
o	Increasing Age  
o	Obesity 
o	Afro-Caribbean 
o	Family history  
o	Dietary factors  
o	Occupational exposure to cadmium
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3
Q

epidemiology of prostate cancer?

A
  • COMMON

* 2nd most common cause of male cancer deaths

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4
Q

what are the presenting symptoms and signs of prostate cancer?

A
  • Often ASYMPTOMATIC
  • Lower Urinary Tract Obstruction
  • Haematuria
  • Pain: back, perineal or testicular
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5
Q

how will prostate cancer present on DRE?

A

hard nodular enlargement with a loss of median sulcus

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6
Q

how does metastatic spread present?

A

o Bone pain
o Cord compression
o Systemic symptoms

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7
Q

initial investigation?

A

PSA

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8
Q

gold standard investigation?

A

• Multiparametric MRI Scan

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9
Q

causes of raised PSA?

A
  • BPH
  • 4 weeks post UTI
  • Prostatitis
  • 48 hours post ejaculation
  • 48 hours post exercise
  • After urinary retention
  • 6 weeks post-surgery
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