Prevention of Ischemic Stroke Flashcards Preview

Phar 505 > Prevention of Ischemic Stroke > Flashcards

Flashcards in Prevention of Ischemic Stroke Deck (16)
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1
Q

What are the risk factors for acquiring a stroke

A

Atrial Fibrillation, Hypertension, Hyperlipidemia/Obesity, Smoking, Diabetes

2
Q

What are the antiplatelet agents used in Secondary Stroke Prevention

A

Asprin, Clopidorel, Aggrenox

3
Q

T/F: 325 mg have better chronic stroke prevention than 81 mg

A

False: There is no verifyable difference in prevention of stroke between an 81 mg dose and a 325 mg dose of aspirin

4
Q

What is the only non oral antiplatelet threapy that can be given for stroke prevention

A

Asprin Suppositories

5
Q

T/F: There is no significant risk reduction in using either aspirin or clopidogrel for secondary prevention of stroke

A

True

6
Q

T/F: Mixing asprin and clopodigrel, regardless of order, has a significant benefit of secondar prevention of stroke

A

False

7
Q

What is in Aggrenox, what is the key counseling point for taking this medication

A

Extended-release dipyridamole (ERD) 200 mg PLUS Aspirin 25 mg/ Do not crush, chew, or open capsule

8
Q

What is the most prominant side effect of Aggrenox that causes low adherence to the medication, what are teh other side effects, what should be counseled about these side effects

A

Headches, diarrhea, abdominal/ headaches should subside after one month, take Aggrenox before bed once a day to start then once tolerated move to twice a day

9
Q

For primary prevention of stroke what combination of antiplatelets should be given minor ischemic stroke or high risk TIA, for how long, what constitutes as minor ischemic stroke and high-risk TIA

A

Clopidogrel PLUS Aspirin started within 24 hours for 21 days then move to monotherapy of just Aspirin/ Minor ischemic stroke = NIHSS score less than or equal to 3, High risk TIA = ABCD2 score greater than or equal to 4

10
Q

What are non modifiable risk factors for stroke

A

Age greater than 55, family history, race (blacks, hispanics/asians, whites), males, prior stroke or TIA

11
Q

What is the hypertension goal of stroke patients, what antihypertensives can be used, when can they be inititeated

A

less than 130/80 mmHG/ diuretics and ACE inhibitors, 24- 48 hours after acute stroke

12
Q

What are goals for all stroke patients with diabetes

A

Fasting glucose less than 126 g/dL, HgbA1c less than 65%, Oral glucose tolerance test less than 200 g/dL

13
Q

T/F: If a patient does not have hyperlipidemia statins have no reason it should be used in secondary prevention of stroke

A

False: High intensity statins are recommended in patients with previous stroke

14
Q

When a patient stops smoking when does the elevated risk of stroke disappear

A

After 5 years

15
Q

Stroke/TIA patients diagnosed with atrial fibrillation should automatically be considered for anticoagulation

A

True

16
Q

When would a person be given an anticoagulation therapy after a stroke, when would they not/ what should be given if they can’t take anticoagulation

A

Within 14 days after stroke unless high risk for hemorrhage, Aspirin alone