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Flashcards in Poisoining Deck (32)
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1
Q

Which drugs are activated charcoal especially effective in? (5)

A
  1. Carbamazepine
  2. Dapsone
  3. Phenobarbital
  4. Quinine
  5. Theophylline
2
Q

S&S: Alcohol

A

Movement, brain

e.g. ataxia and nystagmus

3
Q

S&S: Aspirin

A

Deafness & Tinnitus

4
Q

Treatment Options: Aspirin (3)

A
  1. Activated charcoal
  2. Sodium bicarbonate
  3. Dialysis
5
Q

S&S: Opioids

A

Respiratory depression & Pinpoint pupils

6
Q

Treatment: Opioids

A

Naloxone

7
Q

S&S: Paracetamol

A

Initially: Just nausea and vomiting
Later: Encephalopathy, haemorrhaging, cerebral oedema

8
Q

Treatment: Paracetamol

A

IV Acetylcysteine - 3 consecutive infusions

9
Q

S&S: TCAs

A

Dry mouth

10
Q

Treatment: TCAs (3)

A
  1. Charcoal
  2. Sodium bicarbonate
  3. IV Lorazapam
11
Q

S&S: SSRIs

A

Tremor, nystagmus, sinus tachycardia

Serotonin syndrome:

  • Confusion, agitation, restlessness
  • Sweating, HYPERthermia, HYPERtension
12
Q

Treatment: SSRIs (2)

A
  1. Charcoal

2. IV lorazapam

13
Q

S&S: Antipsychotics

A
  • Movement disorders (can be at therapeutic doses)

- Arrhythmias, Convulsions, ECG

14
Q

Treatment: Antipsychotics (2)

A
  1. Charcoal

2. Procyclidine for EPSEs

15
Q

S&S: BDZ

A

Drowsiness, Movement disorders & Respiratory depression

16
Q

Treatment: BDZ

A

Charcoal & Flumazenil (specialist)

17
Q

S&S: Beta blockers

A

Bradycardia, Lightheadedness & Hypotension, Hypoglycaemia

18
Q

Treatment: Beta Blockers

A
  1. Atropine

2. IV Glucagon

19
Q

S&S: Calcium channel blockers

A

Hypotension, Heart Block, Arrythmias

20
Q

Treatment: Calcium channel blockers (4)

A
  1. Charcoal
  2. Calcium chloride / Calcium gluconate
  3. Atropine
  4. Insulin and glucose
21
Q

S&S: Iron Salts

A

Abdominal pain, vomiting blood & rectal bleeding

22
Q

Treatment: Iron Salts

A

Desferrioxamine mesilate

23
Q

Causes: Lithium (4) - Reduced excretion

A
  1. Dehydration
  2. Renal function deterioration
  3. Infections
  4. Co-administration with NSAIDs/Diuretics
24
Q

S&S: Lithium

A

Weakness, Muscle tremor, Electrolyte imbalance, Dehydration, Hypotension

25
Q

Treatment: Lithium (3)

A
  1. Haemodialysis
  2. Fluids
  3. Gastric lavage
26
Q

S&S: Cocaine, ecstasy, amfetamines

A

Wakefulness, Paranoia & Hallucinations

27
Q

Managment: Cocaine, ecstasy, amfetamines

A

Diazepam

For ecstasy - methylenedioxymethamfetamine

28
Q

S&S: Theophylline

A

Fast and sick

29
Q

Management: Theophylline (5)

A
  1. Repeated doses of charcoal (MR)
  2. Ondansetron for vomiting
  3. IV potassium chloride
  4. IV lorazapam
  5. Short acting beat blocker
30
Q

Management: Digoxin

A

Digifab

31
Q

Management: Dabigatran

A

Idarucizumab

32
Q

Management: Warfarin

A

Vitamin K (PHYTOMENADIONE)