Pharmacology - Chapter 91 - Antifungal Agents Flashcards Preview

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Flashcards in Pharmacology - Chapter 91 - Antifungal Agents Deck (9)
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1
Q

What are the two major groups of antifungal disease?

A
Systemic Mycotic (fungal) infections, which are much less frequent and more dangerous.
Superficial Mycotic (fungal) infection.
2
Q

What are the two types of Systemic Mycotic infections?

A

Opportunistic and Non-opportunistic.

3
Q

Opportunistic - primarily in….

A

debilitated and immunocompromised hosts.

4
Q

Systemic mycotic (fungal) infections are easy to treat. T/F?

A

False - they are difficult to treat!

5
Q

What are the four classes of systemic antifungal drugs?

A

Polyenes, Azoles, Pyrimidine Analogs, Echinocandins.

6
Q

Amphotericin B (Fungizone) - it is a ___ spectrum fungal agent that is used for..

A

Broad spectrum/systemic mycoses.

7
Q

Fungistatic - def

A

inhibits the synthesis of ergosterol, which is an essential component of the fungal cytoplasmic membrane, which causes leakage, etc.

8
Q

What are some adverse effects of the Azole group of antifungal agents?

A

Nausea, Headache, Vomiting, Abdominal pain.

9
Q

Superficial mycoses are caused by two groups of fungi -

A

Candida Species and Dermatophytes

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