PHARMACOKINETICS AND DRUG ADM PART B Flashcards Preview

PHARMA I > PHARMACOKINETICS AND DRUG ADM PART B > Flashcards

Flashcards in PHARMACOKINETICS AND DRUG ADM PART B Deck (4)
Loading flashcards...
1
Q

the amount of drug eliminated per unit time is proportional to the plasma concentration of the drug
-20% of the drug eliminated per hour

A

first order elimination (concentration-dependent)

2
Q

elimination rate is fixed to an amount of drug per unit time
i.e. 20 mg of drug eliminated per hour

A

zero order elimination

3
Q

this describes enzymatic reactions where a maximum rate of reaction is reached when drug concentration achieves 100% enzyme saturation

A

Michaelis-menten kinetics

4
Q

single large dose of a drug that is used to raise the plasma concentration to a therapeutic level more quickly than would occur through repeated smaller doses

A

loading dose

Decks in PHARMA I Class (138):