Pharm- Platelet inhibitors Flashcards Preview

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Flashcards in Pharm- Platelet inhibitors Deck (9)
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1
Q

Ticlopidine- Indications

A

Prevention of TIA, strokes for patient with previous events, with aspirin to prevent thrombus

2
Q

Ticlopidine- MOA

A

Block platelet aggregation by inhibiting binding of ADP to receptors- prevent platelets from binding to fibrinogen and each other

3
Q

Ticlopidine- AE

A

hematologic, thrombocytic purpura, aplastic anemia, neutropenia

4
Q

Clopidrel- Indications

A

Prevention of artherosclerotic events following MI, stroke, peripheral artery disease, prevention of thrombotic events

5
Q

Clopidrel- MOA

A

Block platelet aggregation by inhibiting binding of ADP to receptors- prevent platelets from binding to fibrinogen and each other

6
Q

Clopidrel- AE

A

thrombotic throbocytopenic purpura, poor metabolizers,

7
Q

Aspirin- Indications

A

Prophylaxis of ischemia, MI. Prevention of clotting

8
Q

Aspirin- MOA

A

Irreversibly inhibits COX 1- reduces prostaglandin, and thrombaoxane. Reduces platelet aggregation

9
Q

Aspirin- AE

A

Increased bleeding time, GI bleeds