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Flashcards in Pharm- Platelet inhibitors Deck (9)
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1

Ticlopidine- Indications

Prevention of TIA, strokes for patient with previous events, with aspirin to prevent thrombus

2

Ticlopidine- MOA

Block platelet aggregation by inhibiting binding of ADP to receptors- prevent platelets from binding to fibrinogen and each other

3

Ticlopidine- AE

hematologic, thrombocytic purpura, aplastic anemia, neutropenia

4

Clopidrel- Indications

Prevention of artherosclerotic events following MI, stroke, peripheral artery disease, prevention of thrombotic events

5

Clopidrel- MOA

Block platelet aggregation by inhibiting binding of ADP to receptors- prevent platelets from binding to fibrinogen and each other

6

Clopidrel- AE

thrombotic throbocytopenic purpura, poor metabolizers,

7

Aspirin- Indications

Prophylaxis of ischemia, MI. Prevention of clotting

8

Aspirin- MOA

Irreversibly inhibits COX 1- reduces prostaglandin, and thrombaoxane. Reduces platelet aggregation

9

Aspirin- AE

Increased bleeding time, GI bleeds