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Pharmacology > PDT > Flashcards

Flashcards in PDT Deck (17)
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1
Q

ALA requires occlusion

A

F

2
Q

ALA is more hydrophilic than MAL

A

T

3
Q

Application of ALA does not require occlusion

A

T

4
Q

MAL requires premixing before use

A

False

5
Q

MAL uses red light

A

T

6
Q

MAL is converted to ALA by esterases

A

T

7
Q

MAL is available in a cream

A

T

8
Q

ALA and MAL are category C

A

T

9
Q

When ala is exogenously the control point is bypassed and ala is metabolized along the Haem
Pathway , inducing accumulation of porphyrins (esp protoporphyrin IX)

A

T

10
Q

ALA and MAL are highly flourescent

A

F

As opposed to their precursors MAL and ALA, non metal bound porphyrins are highly fluorescent

11
Q

Both ALA and MAL PDT are used off label in to of acne

A

T

12
Q

Allergy to peanut and almond oil contraindicates use of ALA

A

F

MAL Cream contains these

13
Q

MAL is contraindicated in porphyria

A

T

14
Q

Sun exposure on treated lesion sites and peripheral skin should be avoided for 24h after topical app of MAL and ALA

A

F

48h

15
Q

When ALA-PDT is used on large skin surfaces with shorter application time , photo toxic reaction is more intense

A

F

Less intense

16
Q

With ALA PDT, eodema May last up to one week and erythema up to 2 weeks .

A

T

17
Q

Prolonged facial erythema can occur for few months but is rare following PDT

A

t