Pain treatment lecture 1 Flashcards
What factors should you consider when determining selection of analgesic?
- Type of pain
- Pain intensity
- Side effects and vulnerabilities
What are the two types of pain?
- Musculoskeletal (somatic)
- Inflammatory
- Visceral pain
In the brain what are ways to manage pain?
- Opioid narcotics
- Glutamate/GABA (Ultram)
- Antidepressants (5HT/NE)
In the dorsal horn how can you manage pain?
- Local anesthetic
- Opioids
- NSAIDs
In the peripheral nociceptors how can you manage pain?
- Local anesthetic
- NSAIDs
- Acetaminophen
- Capsaicin
What are non-selective COX 1 and 2 inhibitors?
- Salicylates
- Ibuprofen like
What are selective COX 2 inhibitors?
-Celebrex (Celecoxib)
There is a higher amount of heart attacks and strokes with which type of NSAID?
-Cox 2 inhibitor
What does the COX 1 enzyme do?
- Provide protection for Gastric mucosal barrier
- Renal function
- Platelet aggregation
- Vasoconstriction
What type of pain medication does not interact with ulcers even though they are an NSAID?
-COX 2 inhibitors
What can cause Ulcers/GI problems?
-COX 1 inhibitors
What can cause bleeding problems?
-COX 1 inhibitors
What pain medications should you not use if a pt has a history of cardiovascular disease?
-COX 2 inhibitors
If a person has kidney disease what should you not give them for pain medication?
-COX 1 and 2 inhibitors
If a person has Reye’s syndrome what should you avoid?
-Salicylates in children
