Other Teratogens

Question 1

Ionizing Radiation (2)

Answer 1

• CNS malformations (early exposure)

- malignancy (late exposure)

Question 2

Excess Vit A (4)

Answer 2

• spontaneous abortion
• microcephaly
• cardiac defects
• can interfere with neural cell migration or HOX gene expression

Question 3

Maternal DM (3)

Answer 3

• cardiac defects
• neural tube defects
• caudal regression syndrome

Question 4

Maternal Iodine? Def

Answer 4

congenital hypothyroidism (cretinism)

Question 5

Nicotine (3)

Answer 5

• placental abruption
• low birth weight
• IUGR

Question 6

Cocaine (3)

Answer 6

• placental abruption
• low birth weight
• IUGR

Question 7

ETOH

Answer 7

fetal alcohol syndrome