Osteoarthritis Drugs Flashcards

1
Q

the drug of choice for osteoarthritis is dependent on what?

A

severity of disease and presence/absence of local inflammatory changes

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2
Q

what are the drugs for osteoarthritis

A

GOT CAND

Glucocorticoids
Opioids
Tramadol
Capsaicin
Acetaminophen
NSAIDs
Duloxetine
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3
Q

first line for mild to moderate osteoarthritic pain without signs/symptoms of inflammation

A

acetaminophen

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4
Q

when do you use NSAIDs for osteoarthritis

A

if acetaminophen is not satisfactory or there are signs/symptoms of inflammation

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5
Q

topical gel or solution for local treatment of osteoarthritis

A

Diclofenac

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6
Q

what is Duloxetine in terms of osteoarthritis

A

selective SNRI used for chronic musculoskeletal pain

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7
Q

opioids used as last resort for intractable osteoarthritic pain

A

hydrocodone
morphine
oxycodone

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8
Q

when is Capsaicin used

A
  • patients with inadequate benefit from NSAIDs
  • patients that can’t tolerate NSAIDs
  • when contraindications to use of NSAIDs
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9
Q

adverse effects of Capsaicin

A
  • severe skin burns and nerve damage at site of application

- dried residue can cause coughing, sneezing, eye irritation

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10
Q

glucocorticoids used when one or few joints affected by osteoarthritis

A

Betamethasone

Triamcinolone

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