Oncology - STS, HS, Mammary Flashcards Preview

Small Animal Medicine > Oncology - STS, HS, Mammary > Flashcards

Flashcards in Oncology - STS, HS, Mammary Deck (79)
Loading flashcards...
1

What are soft tissue sarcomas?

Mesenchymal tumors/spindle cell tumors - it is an umbrella term

2

What tumors are soft tissue sarcomas?

Fibrosarcoma, peripheral nerve sheath tumor, myxosarcoma, liposarcoma, rhabdomyosarcoma, synovial cell sarcoma, and lymphangiosarcomas

3

Soft tissue sarcomas are typically solitary/in multiples.

solitary

4

What age of dogs and cats typically get soft tissue sarcomas?

older dogs and cats

5

Where else, aside from the skin, can soft tissue sarcomas be seen?

GI tract, liver, and bladder possible

6

What is the behavior of STS?

slow growing/insidious onset

7

STS are __________.
a. not encapsulated
b. pseudoencapsulated
c. encapsulated

b. pseudoencapsulated

8

What grade of STS are more likely to recur and metastasize?

Grade III

9

What size STS generally have a poor response to chemo and/or radiation?

Bulky tumors - >5cm

10

Is an FNA or a biopsy preferred for STS diagnosis?

biopsy

11

What type of biopsy is preferred for STS diagnosis?

incisional - can be misleading

12

How do you need to position your biopsy for STS?

Position so that the biopsy tract is removed with surgery

13

What is staging for STS based on?

Minimum database, FNA local lymph node, 3 view chest rads and CT scan for surgical planning

14

What makes STS tumors especially difficult to excise?

They have spindles that can spread out from the tumor

15

What is grading of STS based on?

differentiation, mitosis, and necrosis

16

What treatment can be done for STS?

Wide surgery, +/- radiation therapy, +/- chemotherapy

17

What margins do you want for STS?

3cm lateral and 1 fascial plane

18

What may make it difficult to get complete excision for STS?

Less likely if >5 cm
Deep location
Invasive

19

Can STS recur after surgery?

Yes, the potential for recurrence is greater with a greater grade

20

If you chose not to do wide therapy for STS, what are the other options?

Amputation/hemipelvectomy or marginal excision with radiation therapy

21

When you take a STS out, what do you want to do before placing it into formalin?

pin it out and ink to help prevent shrinkage in formalin

22

What type of radiation do you want to use with STS if you got marginal excision?

Definitive radiation
Stereotactic doesn't seem to work as well

23

What side effects are associated with definitive radiation for STS?

Acute skin effects and a long term potential for secondary tumors

24

What is the chemotherapy agent of choice for STS? When is it indicated?

Doxorubicin
Indicated for grade III STS

25

What is the average time to metastatic disease development from STS diagnosis?

1 year

26

What are the negative prognostic factors for recurrence of STS?

Large tumor size, incomplete excision, and high grade

27

What are the negative prognostic factors for metastatic disease of STS?

Grade, necrosis, mitotic index, and local regrowth

28

What is the MST for dogs with a grade I STS?

48 months

29

What is the MST for dogs with a grade II STS?

17 months

30

What is the MST for dogs with a grade III STS?

7.8 months

Decks in Small Animal Medicine Class (100):