Oncology - Oral and Nasal Flashcards Preview

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Flashcards in Oncology - Oral and Nasal Deck (65)
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1

What is the most common oral tumor in the dog?

Melanoma

2

What oral tumors do dogs get?

Melanoma, SCC, fibrosarcoma, acanthomatous ameloblastoma

3

What nasal tumors do dogs get?

adenocarcinoma

4

What history is often associated with oral tumors in dogs?

Halitosis, blood in the water bowl, ptyalism, dysphagia, and hyporexia

5

When you are trying to diagnose canine oral tumors, what do you want to examine in the mouth?

Mandible, maxilla, palate, tongue, under the tongue, tonsils, and palpate under the mandible and between the rami

6

True or False: All oral tumors look the same.

False - they can be raised, pignmented, ulcerated, smooth, and friable

7

What is the first diagnostic test you want to do, aside from PE, when you have an oral neoplasia?

minimum database

8

You should aspirate one/both regional LN in patients with an oral mass.

both - even if they could look normal

9

True or False: FNA is better for diagnosing oral tumors.

False - biopsy is best

10

What imaging methods should you do if you are dealing with an oral tumor?

Chest x-rays to look for metastasis, +/- dental rads, and CT scan

11

Oral malignant melanomas are tumors of the _______.

melanocytes

12

Where are oral melanomas most commonly seen?

Gingiva, lips, tongue, and hard palate

13

True or False: Not all oral melanomas are pigmented

true - 1/3 of them are not

14

How do oral melanomas typically look in the mouth (not color)?

ulcerated and necrotic

15

What does the biological behavior of oral melanomas depend on?

size, site, and histologic parameters

16

Oral melanomas are ______ invasive with a high _______ potential.

Locally, metastatic

17

How can oral melanomas be treated?

Surgery, radiation, chemotherapy, COX 2 inhibition, and the melanoma vaccine

18

Does a patient have a better prognosis if it gets surgery alone or surgery with radiation therapy?

surgery with radiation therapy

19

Does the stage of oral melanoma affect the survival time?

Yes, the worse the stage, the shorter survival time

20

What are some negative prognostic factors for oral melanomas?

Incomplete surgical margins, locations, and surgery alone

21

Is radiation alone or radiation with surgery associated with a longer survival time in oral melanoma patients?

radiation with surgery

22

What is the only chemotherapy that oral melanoma is responsive to?

Carboplatin - still not very responsive

23

What drug can inhibit COX2 and aid in treatment of oral mealnoma?

Piroxicam

24

What stages of oral melanoma is the melanoma vaccination licensed for?

stage II/III with local control

25

True or False: The oral melanoma vaccination can be used to prevent oral melanoma.

False

26

What is the oral melanoma vaccination made out of?

Gene for human tyrosinase is inserted into a DNA plasmid

27

What does the oral melanoma vaccination do?

Stimulates the immune system to the presence of the tyrosinase and targets melanoma cells

28

Large/small breeds more often get canine fibrosarcoma.

Large

29

60-72% of fibrosarcomas have ____ involvement.

bone

30

How are fibrosarcomas typically treated?

Surgical treatment and radiation treatment

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