Oncology Flashcards Preview

Absite Review > Oncology > Flashcards

Flashcards in Oncology Deck (26)
Loading flashcards...
1

Tumor marker: CA 125

epithelial ovarian cancer (can be elevated in endometriosis, uterine myomas, salpingitis, PID)

2

Tumor marker: hCG

embryonal cell carcinomas
ovarian choriocarcinomas
seminoma
mixed germ cell
some dysgerminomas

3

Tumor marker: AFP

Yolk sac tumors
embryonal cell carcinomas
mixed germ cell
some immature teratomas

4

Tumor marker: LDH

Dysgerminoma

5

Tumor maker: Inhibin

epithelial stroma tumors: mucinous and endometrioid carcinoma
sex cord stromal tumors: granulosa cell tumor and sertoli leydig cell tumor

6

what is the most common genetic alteration in pancreatic cancer?

k-ras (80-100% of panc ca), oncogene

7

genetic mutation: DPC4

pancreatic cancer (50% of panc ca) (tumor suppressor genes)

8

MOA imatinib and what is it used for?

tyrosine kinase inhibitor used in GISTS: NAC = mets or unresectable, adjuvant = high risk features

9

what is seen on endoscopic US for GIST?

hypoechoic solid tumor continuous with muscularis mucosa, round submucosal lesion in stomach

10

which cancer is the most sensitive to radiation therapy?

seminoma

11

colon cancer RARELY mets to bone- what is mechanism when it does?

isolated mets to sacrum or vertebral bodies when tumor emboli travel though Batson plexus (portal-vertebral venous communications)

12

Name cancer assoc: HTLV type 1

adult t cell leukemia

13

Name cancer assoc: EBV

Burkitt lymphoma, B cell lymphoma, nasophayngeal cancer

14

Name cancer assoc: hep B

HCC

15

Name cancer assoc: hep c

HCC

16

Name cancer assoc: h pylori

MALT: mucosa assoc lymphoid tissue lymphoma

17

treatment of MALT lymphoma?

Stage 1 and 2: triple/quadruple therapy for h pylori
High grade, Stag III or IV: CHOP +/- radiation

18

Name cancer assoc: vinyl chloride

hepatic angiosarcoma

19

Name the chemotherapy agent: hemorrhagic cystitis

cyclophosphamide

20

Name the chemotherapy agent: cardiomyopathy

doxorubicin/daunorubicin

21

Name the chemotherapy agent: neurotoxicity

vincristine

22

Name the chemotherapy agent: pulmonary fibrosis

bleomycin

23

Name cancer assoc: HPV

anal cancer and cervical

24

Name cancer assoc: HHV-8

kaposi's sarcoma

25

management of malignant fibrous histiocytoma of bone?

NAC + wide margin excision (urgent resection if high risk for pathologic fx)

26

most common cancer to metastasize to small bowel?

melanoma