Flashcards in Muscle Relaxants Deck (11)
What do muscle relaxants do?
Neuromuscular blocking agents that interrupt transmission of impulses from motor nerve to muscle synapse
They act at the nicotinic receptor to block release acetylcholine
What are the two kinds of muscle relaxants
Depolarising and non-depolarising
What do depolarising muscle relaxants do?
Cause initial surge at neuromuscular followed by refractory period where muscle dose not respond - binds straight to post synaptic receptors
Name a depolarising muscle relaxant
What do non-polarising muscle relaxants do
Block receptors at the muscle end plates
Name a non-polarising drug
Which kind of muscle relaxant can be reversed?
Do muscle relaxants affect consciousness
no - they do not cross the blood brain barrier
Do muscle relaxants provide analgesia
Why use muscle relaxants? (name 2 reasons)
- facilitate controlled IPPV
- During intraocular surgery
- Where good muscle relaxation is required to facilitate the surgery
- As part of a balanced anaesthesia technique for high risk patients