Muscle Relaxants Flashcards Preview

Veterinary Nursing Anaesthesia and Analgesia > Muscle Relaxants > Flashcards

Flashcards in Muscle Relaxants Deck (11)
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1

What do muscle relaxants do?

Neuromuscular blocking agents that interrupt transmission of impulses from motor nerve to muscle synapse
They act at the nicotinic receptor to block release acetylcholine

2

What are the two kinds of muscle relaxants

Depolarising and non-depolarising

3

What do depolarising muscle relaxants do?

Cause initial surge at neuromuscular followed by refractory period where muscle dose not respond - binds straight to post synaptic receptors

4

Name a depolarising muscle relaxant

Succinylcholine
Suxamethonium

5

What do non-polarising muscle relaxants do

Block receptors at the muscle end plates

6

Name a non-polarising drug

vescuronium
atracurium

7

Which kind of muscle relaxant can be reversed?

Non-polarising

8

Do muscle relaxants affect consciousness

no - they do not cross the blood brain barrier

9

Do muscle relaxants provide analgesia

no

10

Why use muscle relaxants? (name 2 reasons)

- facilitate controlled IPPV
- During intraocular surgery
- Where good muscle relaxation is required to facilitate the surgery
- As part of a balanced anaesthesia technique for high risk patients

11

Name 2 disadvantages of muscle relaxants

- hypothermia due to decreased muscle tone
- difficult to assess anaesthetic depth
- some drugs in this group may cause hypotension
- Increased effects if used with aminoglycosides
- Increased susceptibility if used alongside halothan, isoflurane, corticosteroids, some diuretics, and epinephrine
- Very vigilant monitoring is necessary during and post anaesthetic period due to laryngeal muscles