Monoclonal Antibodies (P1) Flashcards Preview

Biology > Monoclonal Antibodies (P1) > Flashcards

Flashcards in Monoclonal Antibodies (P1) Deck (8)
Loading flashcards...
1
Q

Antibodies

A

Bind to antigens on pathogens
Made by B-lymphocytes
Either damage pathogens or stick them together

2
Q

How do they work

A

Immunise a mouse by injecting it to produce the B-lymphocytes for the disease
Remove the B-lymphocytes from the mouse
Fuse them with tumour cells to make hybridoma cells
Leave the cells to reproduce and form many cells

3
Q

Advantages

A

Can cure a disease
Bind to cancer cells
Can bind to many antigens as there are so many

4
Q

Disadvantages

A

Time consuming
Expensive
Only bind to one antigen

5
Q

What are they

A

Identical copies of an antibody reproduced for one antigen

6
Q

Hybridoma

A

A cell used for the large scale production of antigens

7
Q

Uses of monoclonal antibodies

A

Pregnancy test (HCG hormones in urine)
Diseases such as herpes and chlamydia
Carry drugs directly to tumours
Detect HIV

8
Q

How do they stop cancer cells?

A

Antibodies attach to antigens, releasing hormones to slow the growth
It attaches to the antigen and signals to white blood cells to destroy the cancer cell
Chemical or radioactive substances attached to the antibody destroy it