Mitosis Flashcards Preview

Human Genetics > Mitosis > Flashcards

Flashcards in Mitosis Deck (18)
Loading flashcards...
1
Q

Check point

A

controlled by a gate keeper genes which act like guards and require a signal to go to the next phase

2
Q

Cyclin

A

family of proteins that control cells through cell cycle like kineases

3
Q

maturation promoting factors

A
  • start mitosis by dissolving the nuclear membrane
  • condense chromatin
  • begin spindle fiber formation
  • degrade cyclin
4
Q

Gaps

A

G1- allows cell to go to synthesis
G2-regulates passage into mitosis ensures proper DNA replication
G0-no signal where they do not replicate

5
Q

Survivan

A

produced to allow cell to survive, without these proteins cell can go into apoptosis

6
Q

cohesion

A

act of sticking together to form a whole

7
Q

differentiated

A

specialized cell growth- normal somatic cells

8
Q

contact inhibition

A

cells know when to stop growing when the size has been filled

9
Q

Hayflick Limit

A

telomeres shorten with each nuclear division limiting the number of possible DNA replications

10
Q

telomerase

A

prevents the shortening of telomeres

11
Q

cellular adhesion molecules

A

CAMS allow binding with other cells or with the extracellular matrix

12
Q

metastasize

A

cells break off and go everywhere because no cams so they break off to other organs

13
Q

progeria, progerin

A

rapid aging due to errors due to defects in DNA repair mechanisms bc of high level of protein progerin
-autosomal

14
Q

Werner Syndrome

A

rapid aging which causes premature death after midlife and this is autosomal recessive

15
Q

Achondroplasic Dwarfism

A

mutation of resistant fibroblast growth factor receptors in long bone cells growth stunts mitosis
dominant

16
Q

mitosis

A

PMAT- division of somatic cells only, for growth and repair

17
Q

Interphase

A

G1, S, G2

18
Q

Cytokinesis

A

cleavage furrow forms through actin and myosin and cytoplasm divides