Microbiology Gram Negative Bacterial Diseases Flashcards

1
Q

Gm negative have cell walls?

A

yes

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2
Q

What are our gram negative Cocci

A

Neisseria Meningitidis

N. Gonorrhoeae

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3
Q

Gram negavtive coccoid rods

A

H. Influenzae

Bordetella Pertussis

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4
Q

Oxidase positive comma shapped that crows in 42 degrees celcius

A

Campylobacter Jejuni

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5
Q

Oxidase positive that grows in alkaline media

A

vibrio cholerae

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6
Q

What are our gm - rods that are lactose fermentors

A

Klebsiella

E.coli

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7
Q

What are the gram negative rods that do not ferment lactose

A

Pseudomonas
Shigella
Salmonella
Proteus

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8
Q

What gm - rods are oxidase positive

A

Psudomonas

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9
Q

What Gm- rods are oxidase negative

A

Shigella
Salmonella
Proteus

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10
Q

What are the virulence factors of neisseria

A
FImbria
Capsule
Protease (inhibit IgA)
Lipid A endotoxin
Oxidase positive
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11
Q

What does it mean to be oxidase positive

A

use oxygen from ETC = aerobe

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12
Q

What enviornment does neisseria thrive in

A

CO2 rich

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13
Q

Neisseria meningitidis has what virulence factors

A

Capsule made of N-acetylneuramininic acid

LOS: lipid A

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14
Q

What diseases does niesseria meningitidis cause and in what demographic

A

Meningitis

Septicemia/death

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15
Q

Where can neisseria gonorrhoeae replicate

A

In WBC’s

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16
Q

What diseases does N. gonorrhoeae cause

A

STI
Septic Arthritis
PID
Neonatal conjunctivitis

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17
Q

What type of medium do you grow Neisseria on

A

Chocolate and Thayer-Martin

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18
Q

What are the main characteristics of Klebsiella pneumoniae

A
  • It is a fast lactose fermentor
  • capsule (quelling reaction) swelling

-Mostly Nosocomial

19
Q

Diseases that Klebsiella causes

A
  • UTI (hospital acquired)

- Pneumonia (diabetic, alcoholic)

20
Q

Red current jelly sputum is what organism

A

Klebsiella

21
Q

What is the main type of entero hemorrhagic E. Coli

A

0157:H7

22
Q

What are the main pathogenicities for E. coli

A

Plasmids
Shiga like toxin
Type III secretion system

23
Q

What syndrome can E.coli cause

A

Hemolytic Uremia Syndrome

24
Q

What are the main characteristics of Shigella

A

-Nonmotile
Cell to Cell transmission
Doesnt Ferment Lactose
Urease and Oxidase negative

25
Q

What are the 4 F’s and what bug are they associated with

A

Food, Finger, Feces, Flies

Shigella

26
Q

What toxin and what disease does shigella cause

A

has endotoxin and
Exotoxin: Shiga toxin
Watery bloody mucuousy didysentery

27
Q

What is the main characteristics of salmonella

A

Motile

Urease and oxidase negative

28
Q

What is the main sequella of Salmonella

A

Typhoid fever from S. typhi

Gastroenteritis, bactermeia, peritonitis

29
Q

Rose spots on abdomen, Fever, headache, diarrhea or constipation think

A

typhoid fever

30
Q

What type of E. coli has LT (heat labile) and ST(heat stable) proteins

A

Enterotoxigenic (ETEC)

31
Q

what are the main characteristics of preoteus

A

Urease Positive
Oxidase negative
Flagella make it very motile

32
Q

What two diseases do proteus cause

A

UTI

Kidney Stones

33
Q

Why does urease lead to kidney stones

A

takes acid and makes base (ammonia) leads to struvite stones

34
Q

Main characteristics of Pseudomonads

A

Oxidase Positive
Produces Blue-green pigment
Grape like odor

35
Q

Diseases pseudomonads cause

A
  • Wound and burn infections

- Hot tub foliculitis

36
Q

What diseases does Pseudomonas aeruginosa cause

A

-Pneumonia: cystic fibrosis patients and immunocompromised

Ostemyelitis: dibetetic and IV drugs

  • Burn wound infections
  • UTI/pylo in nursing home hospital aquired
  • Endocarditits in IV drug users
37
Q

What are the two types of cocobacillus

describe them

A

Haemophilus and bordetella

Shape between rod and cocci

Anerobic

38
Q

What is the main pathogeniciy of Haemophilus Influenzae

A
  • Capsule B= bad

- IgA protease

39
Q

What diesaes does Haemophilis influenzae cause

A

-Meningitis
-Epiglottitis
Oneumonia

40
Q

What does Haemophilis ducreyi cause

A

painful genitial ulcer (chanchroid)

Painful inguinal lymphadenopathy

41
Q

What is the epidemiology and pathogenicity of bordetella

A

Inhibits ciliary action
Adhesins
Toxins

42
Q

What are the toxins of bordetella

A

Pertussis
adenylate cyclase
dermonecrotic
tracheal

43
Q

what type of culture do you grow bordetella in

A

regan-lowe agar

44
Q

what are the three stages of whooping cough

A
  • Catarrhal stage (non descript URI)
  • Paryoxysmal stage ( non productive cough with whoop, vomiting cyanosis)
  • Convalescent stage (less severe persistent cough)