Medical Complications of Addiction Flashcards Preview

Brain and Behavior Part 2 > Medical Complications of Addiction > Flashcards

Flashcards in Medical Complications of Addiction Deck (20)
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1
Q

5 broad, easily recognizable signs/symptoms of addiction?

A
Tolerance
Withdrawal
Cravings
Continued use despite negative consequences
Using more than intendended
2
Q

4 broad, more subtle signs/symptoms of addiction?

A

Denial
Rationalization
Failure to meet obligations
Failure of normal social functioning

3
Q

What’s the success rate for treatment of addiction when defined as “reduction in drug use”?

A

40-60%

4
Q

Sequelae common to oral drug use? (name 3)

A

Gastritis, ulcers, GI bleeding

5
Q

Sequelae common to IV drug use? (name 5)

A
Skin abscesses
Track marks
Blood-borne infections (HIV, Hep C, etc.)
Endocarditis
Emboli
6
Q

Sequelae common to nasal drug use? (name 2)

A

Epistaxis

Ulcers

7
Q

Sequelae common to pulmonary drug use? (name 5)

A
Emphysema
Infarction
Lung collapse
Hemorrhage
Burns
8
Q

Big picture of alcohol withdrawal?

A

Too much glutamate signaling, not enough GABA -> autonomic arousal / seizures.

9
Q

6 signs of fetal alcohol syndrome?

A
Developmental delay / cognitive impairment
Poor impulse control / behavior problems
Learning disabilities
Microcephaly
Vision or hearing problems
Joint deformities
10
Q

How does withdrawal from benzos and barbituates compare to EtOH withdrawal?

A

Very very similar - not enough GABA in brain.

11
Q

Review: Is opiate withdrawal fatal?

A

Nope (unless you have an underlying cardiovascular disease), but it’s miserable.

12
Q

Young person with stroke, MI, renal failure, spontaneous abortion, or bowel ischemia… what should you test for?

A

Stimulants!

13
Q

5 acute effects of stimulant intoxication?

A

CV: vasospasm, increased BP+HR, increased O2 needs.
Electrophysiologcal disturbance -> seizures, arrythmias.
Hyperthermia.
Hyperactivity.
Aggression, paranoia, grandiosity.

14
Q

2 affects of chronic stimulant use?

A

Accelerated atherosclerosis.

Premature aging- i.e. people like like hell.

15
Q

4 long term sequelae of marijuana use?

A

Pulmonary disease
Decreased libido / sperm count
Immunosuppression
Anhedonia

16
Q

PCP and ketamine acute effects? (2 main areas)

A

CV -> increased BP, HR, cardiac output

Psych -> acute psychosis, paranoia, agitation

17
Q

4 acute problems from MDMA (ecstasy)?

A

Hyperthermia, seizures, rhabdomyolsis, liver damage

18
Q

GHB MoA?

A

GHB receptor and GABA receptor agonist.

19
Q

7 acute effects of GHB use?

A

Hypothermia, hypertension, tachycardia, amnesia, nausea/vomiting, seizure, respiratory depression.

20
Q

4 toxicities of inhalants?

A

Seizures, neuropathies.
Liver damage
Cognitive dysfunction
Arrythmias and sudden death.