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Blood and lymph test 2 > Mata > Flashcards

Flashcards in Mata Deck (20)
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1
Q

Heparin

A

Binds with AT3
Irreversibly inactivates thrombin
Neutralized by protamine
Does nothing if you have a AT3 mutation

2
Q

Low Molecular Weight (LMW) Heparins

A

More selective so less side effects/bleeding

Enoxaprine
Dalteparine
Foundiparinoux

3
Q

Heparin toxicity

A

HAT-Heparin interacts with platlets

HIT- Heparin interacts with Abs and can be life threatning

4
Q

Other Anticoags

A

Rivaroxaban (Xarelto®) – Factor X inhibitor

Used to prevent DVT after Sx
Decreases Stroke risk if you have A.Fib

5
Q

Direct thrombin inhibitors

A

End with Rudin

No Reversal agents

Lepirudin
Desirudin
Bivalirudin

6
Q

Small Direct thrombin inhibitors

A

Argatroban- Use if HIT

Dabigatran- no drug interactions

7
Q

WARFARIN (Coumadin®)

A

Against F2/7/9/10 C and S

Drug interactions with sulfonamides and aspirins
CYP2C9 metabolism

8
Q

Clopidine

A

Can be given with loading dose or ASA

Increased CVA if good metabolizer

9
Q

Ticlopidine

A

TTP, Aplastic anemia, neutropenia side fx

10
Q

Prasugrel (Effient®)

A

Don’t give if Hx of TIA/Stroke

11
Q

Ticagelor (Brilinta®)

A

Don’t give if Hx of TIA/Stroke

12
Q

Plasminogen activators

A

Streptokinase (anistreplase)

TPA analogs

13
Q

Plasminogen inactivators

A

Aminocaproic acid

Tranexamic acid

14
Q

Dipyridamole (Persantine®) - oral

A

Dipyridamole + warfarin may be used to prevent thrombus on prosthetic heart valves

Dipyridamole + aspirin : ↓ incidence of thrombotic diathesis in pts.

15
Q

Cilostazol (Pletal®) - oral

A

For PAD and Claudication

Dont give if they have CHF

16
Q

GP2B3A inhibitors

A

Eptiibatide
Abciximab
Tirofiban

17
Q

PDE inhibitors

A

Cilostazol

Dipyridamol

18
Q

Fibrinolytic inhibitors

A

Aminocaproic acid
Tranexemic acid
Amicar

19
Q

Aminocaproic acid

A

After Sx and tooth extractions

And Hemophiliacs

20
Q

Tranexemic acid

A

Used for heavy mensis