Lymphocyte response Flashcards Preview

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Flashcards in Lymphocyte response Deck (4)
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1
Q

Briefly explain Adaptive immunity

A

Lymphocytes – B and T cells

Similar effector mechanisms to innate immunity

Unique, highly specific system of recognition

2
Q

Explain Pathogen recognition in innate immunity

A
  • A fixed repertoire of receptors and soluble molecules (PRR)
  • All components are inherited
  • New variants rarely arise

•Overall strategy
–recognise pathogenic structures (PAMPs), or
–detect alterations in infected or damaged cells

3
Q

Explain Pathogen recognition in adaptive immunity

A

•Each lymphocyte (cell) expresses just one molecular type of receptor
–B cells – B cell Receptor (BCR; membrane immunoglobulin)
–T cells – T Cell Receptor (TCR)

•The receptors are made by gene rearrangement so we all have millions of different specificities
–Each cell is a clone with a unique receptor

4
Q

What are the 3 advantages of adaptive immunity?

A

–Precise, highly specific targeting

–Memory cells

–Recognize “new” pathogens