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Flashcards in Lung Cancer Deck (22)
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1

The prevalence of lung cancer is low. True/False?

True
Incidence is high, but patients do not live for very long

2

What symptom arises due to damage of the recurrent laryngeal nerve?

Hoarse voice

3

Pancoast tumours typically affect which part(s) of the lung?

Top

4

Common sites of lung cancer metastases (5)

Liver
Brain
Bone
Adrenals
Skin

5

Which LFT is particularly abnormal in liver metastasis?

Alkaline Phosphatase (ALP)

6

How can hypercalcaemia arise?

Tumour produces a substance which mimics the effects of parathyroid hormone

7

Lung diseases causing clubbing (ABCDEF)

Abscess
Bronchiectasis
Cystic Fibrosis
Don’t say COPD
Empyema
Fibrosis

8

Name the 4 types of lung tumour classifications

Adenocarcinoma
Squamous cell carcinoma
Small cell carcinoma
Large cell carcinoma

9

TTF-1 is expressed only in adenocarcinoma. True/False?

False
Also in small cell carcinoma

10

P63 is expressed in squamous cell carcinoma. True/False?

True

11

Which type of lung cancer has the poorest prognosis?

Small cell carcinoma

12

Which type of lung cancer is responsive to chemotherapy?

Small cell carcinoma

13

What is the treatment of choice for non-small cell carcinoma?

Surgery

14

K-ras and EGFR mutations occur in which type of lung tumour?

Non-small cell cancer

15

What characteristic of small cell carcinoma makes it susceptible to chemotherapy?

Rapid growth

16

Surgery is only indicated if the disease is localised. True/False?

True

17

What cells give rise to small cell carcinoma?

Neuroendocrine cells

18

Small cell carcinomas are more common in non-smokers. True/False?

False

19

Which lung cancer type is more common in non-smokers?

Adenocarcinoma

20

Which is the most common type of lung cancer?

Squamous cell carcinoma

21

How can small cell carcinoma commonly be treated?

Chemotherapy

22

Who gets radical radiotherapy?

Early NSLC patients with adequate lung function but where surgery is not possible