What are some examples of major liver diseases?
Alcohol related liver disease
Non-alcohol fatty liver disease
Autoimmune liver diseases
What are the 5 main groups of viruses that cause viral hepatitis?
Which of the hepatitis viruses are enteric viruses?
A and E
What are enteric viruses?
Ones transmitted by the faecal-oral route
What hepatitis viruses are parenteral?
Hepatitis B, C and D
What does parenteral mean?
Administered elsewhere than the mouth and alimentary canal
What hepatitis viruses cause self-limiting infections?
A and E
What hepatitis viruses cause chronic infections?
B, C and D
What does transmission of hepatitis A occur by?
What is the most common age group infected with hepatitis A?
5 to 14 years
Is the prevalence of hepatitis A increasing or decreasing worldwide?
What is acute disease caused by hepatitis A diagnosed by?
Who are vacines for hepatitis A given to?
Patients with chronic liver disease
Occupational exposure (lab workers)
Men who have sex with men
What are examples of hepatitis B antigens?
Hepatitis surface antigen (HBsAg)
Hepatitis e antigen (HBeAg)
Hepatitis core antigen (HBcAg)
What does hepatitis surface antigen (HBsAg) indicated?
Presence of hep B virus
What does hepatitis e antigen (HBeAg) indicate?
What does hepatitis core antigen (HBcAg) indicate?
What does HBV DNA indicate?
What are examples of HBV antibodies?
What does anti-HBs antibody indicate?
What does IgM anti-HBc indicate?
What does IgG anti-HBc indicate?
What does anti-HBe indicate?
What can hepatitis B infections possible lead to?
Resolution (no further progress) or cirrhosis
What are treatment options for hepatitis B infections?
Oral antiviral drugs
What oral therapies are available for hepatitis B infections?
What can be said about hepatitis C and symptoms?
Is usually asymptomatic
What are LFTs like with hep C infection?
Can be normal
What is the treatment for hepatitis C infection?
IFN-free combination of direct acting antiviral drugs
What kind of virus is hepatits D?
Small RNA virus