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07. Year 2: Alimentary System > Liver Symposium > Flashcards

Flashcards in Liver Symposium Deck (90)
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1

What are some examples of major liver diseases?

Alcohol related liver disease

Viral hepatitis

Non-alcohol fatty liver disease

Autoimmune liver diseases

 

2

What are the 5 main groups of viruses that cause viral hepatitis?

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

3

Which of the hepatitis viruses are enteric viruses?

A and E

4

What are enteric viruses?

Ones transmitted by the faecal-oral route

5

What hepatitis viruses are parenteral?

Hepatitis B, C and D

6

What does parenteral mean?

Administered elsewhere than the mouth and alimentary canal

7

What hepatitis viruses cause self-limiting infections?

A and E

8

What hepatitis viruses cause chronic infections?

B, C and D

9

What does transmission of hepatitis A occur by?

Faecal-oral route

Sexual

Blood

10

What is the most common age group infected with hepatitis A?

5 to 14 years

11

Is the prevalence of hepatitis A increasing or decreasing worldwide?

Decreasing

12

What is acute disease caused by hepatitis A diagnosed by?

IgM antibodies

13

Who are vacines for hepatitis A given to?

Travellers

Patients with chronic liver disease

Haemophiliacs

Occupational exposure (lab workers)

Men who have sex with men

14

What are examples of hepatitis B antigens?

Hepatitis surface antigen (HBsAg)

Hepatitis e antigen (HBeAg)

Hepatitis core antigen (HBcAg)

HBV DNA

15

What does hepatitis surface antigen (HBsAg) indicated?

Presence of hep B virus

16

What does hepatitis e antigen (HBeAg) indicate?

Active replication

17

What does hepatitis core antigen (HBcAg) indicate?

Active replication

18

What does HBV DNA indicate?

Active replication

19

What are examples of HBV antibodies?

Anti-HBs

IgM anti-HBc

IgG anti-HBc

Anti-HBe

20

What does anti-HBs antibody indicate?

Protection

21

What does IgM anti-HBc indicate?

Acute infection

22

What does IgG anti-HBc indicate?

Chronic infection/exposure

23

What does anti-HBe indicate?

Inactive virus

24

What can hepatitis B infections possible lead to?

Resolution (no further progress) or cirrhosis

25

What are treatment options for hepatitis B infections?

Pegylated interferon

Oral antiviral drugs

26

What oral therapies are available for hepatitis B infections?

Lamivudine

Adefovir

Entecavir

Telbivudine

Tenofovir

27

What can be said about hepatitis C and symptoms?

Is usually asymptomatic

28

What are LFTs like with hep C infection?

Can be normal

29

What is the treatment for hepatitis C infection?

IFN-free combination of direct acting antiviral drugs

30

What kind of virus is hepatits D?

Small RNA virus