Flashcards in Lipid Synthesis Deck (13)
What is the first rate limiting enzyme of FA biosynthesis?
What hormone drive FA synthesis?
What hormone drives formation of acetyl CoA and ketone bodies from FAs?
Glucagon and Epinephrine
What is the reaction of the enzyme Acetyl-CoA Carboxylase?
Converts acetyl CoA to malonyl CoA
What is the function of biotin in FA synthesis?
What transports acetyl groups for FA synthesis?
Citrate carries acetyl from the mitochondria to the cytoplasm
What is the allosteric activator of Acetyl-CoA Carboxylase?
What are the allosteric inhibitors of Acetyl-CoA Carboxylase?
Palmitoyl CoA (it is the ultimate product of FA synthesis)
What is the only physiological inhibitor of rate limiting enzyme in fatty acid oxidation?
What will increase the synthesis of Acetyl-CoA Carboxylase?
High Cabohydrate Diet
Fat Free Diet
What will inhibit the synthesis of Acetyl-CoA Carboxylase?
High Fat Diet
What is the function of the fatty acid synthase complex?
Catalyzes the formation of FAs from 1 acetyl CoA and 7 malonyl CoA